Topological scoring of protein interaction networks

Topological scoring of protein interaction networks

Inferring direct protein−protein interactions (PPIs) and modules in PPI networks remains a challenge. Here, the authors introduce an algorithm to infer potential direct PPIs from quantitative proteomic AP-MS data by identifying enriched interactions of each bait relative to the other baits.

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Detalles Bibliográficos
Autores principales: Mihaela E. Sardiu, Joshua M. Gilmore, Brad D. Groppe, Arnob Dutta, Laurence Florens, Michael P. Washburn
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/639b28dd37f34009bb594be0793601cb
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