Alginate-based 3D cell culture technique to evaluate the half-maximal inhibitory concentration: an in vitro model of anticancer drug study for anaplastic thyroid carcinoma

Alginate-based 3D cell culture technique to evaluate the half-maximal inhibitory concentration: an in vitro model of anticancer drug study for anaplastic thyroid carcinoma

Abstract Background Three-dimensional (3D) cell culture methods are identified for simulating the biological microenvironment and demonstrating more similarity to in vivo circumstances. Anaplastic thyroid carcinoma (ATC) is a lethal endocrine malignancy. Despite different treatment approaches, no im...

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Bibliographic Details
Main Authors: Hilda Samimi, Alireza Naderi Sohi, Shiva Irani, Ehsan Arefian, Mojdeh Mahdiannasser, Parviz Fallah, Vahid Haghpanah
Format: article
Language:EN
Published: BMC 2021
Subjects:
Anaplastic thyroid carcinoma
Two-dimensional cell culture
Three-dimensional cell culture
Anticancer drug
Half-maximal inhibitory concentration
Diseases of the endocrine glands. Clinical endocrinology
RC648-665
Online Access:https://doaj.org/article/63a0f3e0635049c38e577fbd611fefb3
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https://doaj.org/article/63a0f3e0635049c38e577fbd611fefb3

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