Runx1-Stat3 signaling regulates the epithelial stem cells in continuously growing incisors

Abstract Rodent incisors grow permanently and the homeostasis of enamel production is maintained by a continuous supply of epithelial progenitors from putative stem cells in the cervical loop. We herein report that Runx1 regulates the Lgr5-expressing epithelial stem cells and their subsequent contin...

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Autores principales: Safiye E. Sarper, Toshihiro Inubushi, Hiroshi Kurosaka, Hitomi Ono Minagi, Koh-ichi Kuremoto, Takayoshi Sakai, Ichiro Taniuchi, Takashi Yamashiro
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/63ae1d58056c49849a85d69800a0577e
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