Novel Small Molecule Inhibitors That Prevent the Neuroparalysis of Tetanus Neurotoxin
Tetanus neurotoxin (TeNT) is a protein exotoxin produced by <i>Clostridium tetani</i> that causes the deadly spastic neuroparalysis of tetanus. It consists of a metalloprotease light chain and of a heavy chain linked via a disulphide bond. TeNT binds to the neuromuscular junction (NMJ) a...
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| Format: | article |
| Langue: | EN |
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MDPI AG
2021
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| Accès en ligne: | https://doaj.org/article/63b35b43dab140a88f7cfa13188faf6a |
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