A role for Dynlt3 in melanosome movement, distribution, acidity and transfer

Aktary et al. identify novel roles for the dynein light chain Dynlt3 in melanosome transport, maturation, and transfer to keratinocytes. They also find that the Wnt/βcatenin signalling pathway controls Dynlt3 levels and thus also contributes to the regulation of melanocyte transport and skin pigment...

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Autores principales:	Zackie Aktary, Alejandro Conde-Perez, Florian Rambow, Mathilde Di Marco, François Amblard, Ilse Hurbain, Graça Raposo, Cédric Delevoye, Sylvie Coscoy, Lionel Larue
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/63bc3c1ea59f4abfb5884cb3200a500b
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spelling	oai:doaj.org-article:63bc3c1ea59f4abfb5884cb3200a500b2021-12-02T13:24:24ZA role for Dynlt3 in melanosome movement, distribution, acidity and transfer10.1038/s42003-021-01917-52399-3642https://doaj.org/article/63bc3c1ea59f4abfb5884cb3200a500b2021-03-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01917-5https://doaj.org/toc/2399-3642Aktary et al. identify novel roles for the dynein light chain Dynlt3 in melanosome transport, maturation, and transfer to keratinocytes. They also find that the Wnt/βcatenin signalling pathway controls Dynlt3 levels and thus also contributes to the regulation of melanocyte transport and skin pigmentation.Zackie AktaryAlejandro Conde-PerezFlorian RambowMathilde Di MarcoFrançois AmblardIlse HurbainGraça RaposoCédric DelevoyeSylvie CoscoyLionel LarueNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Zackie Aktary Alejandro Conde-Perez Florian Rambow Mathilde Di Marco François Amblard Ilse Hurbain Graça Raposo Cédric Delevoye Sylvie Coscoy Lionel Larue A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
description	Aktary et al. identify novel roles for the dynein light chain Dynlt3 in melanosome transport, maturation, and transfer to keratinocytes. They also find that the Wnt/βcatenin signalling pathway controls Dynlt3 levels and thus also contributes to the regulation of melanocyte transport and skin pigmentation.
format	article
author	Zackie Aktary Alejandro Conde-Perez Florian Rambow Mathilde Di Marco François Amblard Ilse Hurbain Graça Raposo Cédric Delevoye Sylvie Coscoy Lionel Larue
author_facet	Zackie Aktary Alejandro Conde-Perez Florian Rambow Mathilde Di Marco François Amblard Ilse Hurbain Graça Raposo Cédric Delevoye Sylvie Coscoy Lionel Larue
author_sort	Zackie Aktary
title	A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
title_short	A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
title_full	A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
title_fullStr	A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
title_full_unstemmed	A role for Dynlt3 in melanosome movement, distribution, acidity and transfer
title_sort	role for dynlt3 in melanosome movement, distribution, acidity and transfer
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/63bc3c1ea59f4abfb5884cb3200a500b
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A role for Dynlt3 in melanosome movement, distribution, acidity and transfer

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