Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma

Abstract Background Osteosarcoma is a malignant tumor of bone and soft tissue in adolescents. Due to its tumor biological behavior pattern, osteosarcoma usually generates poor prognosis. Autophagy is an important self-defense mechanism in osteosarcoma. Methods Cell viability in IC50 testing and reve...

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Bibliographic Details
Main Authors: Jiaming He, Wenkan Zhang, Xiaozhong Zhou, Weiqi Yan, Zhan Wang
Format: article
Language:EN
Published: BMC 2021
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Online Access:https://doaj.org/article/63bf3f15da5c4a68938498d768b4fa9d
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