Aloin induced apoptosis by enhancing autophagic flux through the PI3K/AKT axis in osteosarcoma
Abstract Background Osteosarcoma is a malignant tumor of bone and soft tissue in adolescents. Due to its tumor biological behavior pattern, osteosarcoma usually generates poor prognosis. Autophagy is an important self-defense mechanism in osteosarcoma. Methods Cell viability in IC50 testing and reve...
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Main Authors: | Jiaming He, Wenkan Zhang, Xiaozhong Zhou, Weiqi Yan, Zhan Wang |
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Format: | article |
Language: | EN |
Published: |
BMC
2021
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Online Access: | https://doaj.org/article/63bf3f15da5c4a68938498d768b4fa9d |
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