The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review
Locally advanced vulvar cancer (LAVC) is a challenging disease, requiring multidisciplinary management. The aim of this review is to propose an integrated clinical approach including radiotherapy (RT) in the multidisciplinary management of LAVC to customize the treatment. A review of the literature...
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MDPI AG
2021
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oai:doaj.org-article:63c1b85b8f474c42a4d77aaad39cd2b42021-11-25T17:03:32ZThe Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review10.3390/cancers132257472072-6694https://doaj.org/article/63c1b85b8f474c42a4d77aaad39cd2b42021-11-01T00:00:00Zhttps://www.mdpi.com/2072-6694/13/22/5747https://doaj.org/toc/2072-6694Locally advanced vulvar cancer (LAVC) is a challenging disease, requiring multidisciplinary management. The aim of this review is to propose an integrated clinical approach including radiotherapy (RT) in the multidisciplinary management of LAVC to customize the treatment. A review of the literature was conducted on PubMed, Scopus, and Cochrane library to acquire all relevant studies on RT in LAVC. Based on the available evidence, RT, with or without concurrent chemotherapy, has a relevant role as adjuvant and exclusive treatment or in the neoadjuvant setting. However, multicentric prospective trials are needed to define the best treatment options based on tumor and patient characteristics. A multidisciplinary and multidimensional assessment can also be useful to identify the most suitable approach, considering patients’ age and comorbidities, in view of a better treatment personalization.Luca TagliaferriValentina LancellottaCalogero CasàSimona Maria FragomeniMartina FerioliStefano GentileschiAnna Amelia CarettoGiacomo CorradoBenedetta GuiGiuseppe Ferdinando CollocaMaria Antonietta GambacortaAlessio Giuseppe MorgantiGiorgia GarganeseGabriella MacchiaMDPI AGarticlevulvar cancerradiotherapyreviewNeoplasms. Tumors. Oncology. Including cancer and carcinogensRC254-282ENCancers, Vol 13, Iss 5747, p 5747 (2021) |
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| topic |
vulvar cancer radiotherapy review Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 |
| spellingShingle |
vulvar cancer radiotherapy review Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282 Luca Tagliaferri Valentina Lancellotta Calogero Casà Simona Maria Fragomeni Martina Ferioli Stefano Gentileschi Anna Amelia Caretto Giacomo Corrado Benedetta Gui Giuseppe Ferdinando Colloca Maria Antonietta Gambacorta Alessio Giuseppe Morganti Giorgia Garganese Gabriella Macchia The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| description |
Locally advanced vulvar cancer (LAVC) is a challenging disease, requiring multidisciplinary management. The aim of this review is to propose an integrated clinical approach including radiotherapy (RT) in the multidisciplinary management of LAVC to customize the treatment. A review of the literature was conducted on PubMed, Scopus, and Cochrane library to acquire all relevant studies on RT in LAVC. Based on the available evidence, RT, with or without concurrent chemotherapy, has a relevant role as adjuvant and exclusive treatment or in the neoadjuvant setting. However, multicentric prospective trials are needed to define the best treatment options based on tumor and patient characteristics. A multidisciplinary and multidimensional assessment can also be useful to identify the most suitable approach, considering patients’ age and comorbidities, in view of a better treatment personalization. |
| format |
article |
| author |
Luca Tagliaferri Valentina Lancellotta Calogero Casà Simona Maria Fragomeni Martina Ferioli Stefano Gentileschi Anna Amelia Caretto Giacomo Corrado Benedetta Gui Giuseppe Ferdinando Colloca Maria Antonietta Gambacorta Alessio Giuseppe Morganti Giorgia Garganese Gabriella Macchia |
| author_facet |
Luca Tagliaferri Valentina Lancellotta Calogero Casà Simona Maria Fragomeni Martina Ferioli Stefano Gentileschi Anna Amelia Caretto Giacomo Corrado Benedetta Gui Giuseppe Ferdinando Colloca Maria Antonietta Gambacorta Alessio Giuseppe Morganti Giorgia Garganese Gabriella Macchia |
| author_sort |
Luca Tagliaferri |
| title |
The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| title_short |
The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| title_full |
The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| title_fullStr |
The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| title_full_unstemmed |
The Radiotherapy Role in the Multidisciplinary Management of Locally Advanced Vulvar Cancer: A Multidisciplinary VulCan Team Review |
| title_sort |
radiotherapy role in the multidisciplinary management of locally advanced vulvar cancer: a multidisciplinary vulcan team review |
| publisher |
MDPI AG |
| publishDate |
2021 |
| url |
https://doaj.org/article/63c1b85b8f474c42a4d77aaad39cd2b4 |
| work_keys_str_mv |
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