Hierarchical composition of reliable recombinase logic devices

Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system.

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Detalles Bibliográficos
Autores principales: Sarah Guiziou, Pauline Mayonove, Jerome Bonnet
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/63c2e554199d49ea9e97726d6bdde83c
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Descripción
Sumario:Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system.