Hierarchical composition of reliable recombinase logic devices
Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system.
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Nature Portfolio
2019
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oai:doaj.org-article:63c2e554199d49ea9e97726d6bdde83c2021-12-02T16:57:51ZHierarchical composition of reliable recombinase logic devices10.1038/s41467-019-08391-y2041-1723https://doaj.org/article/63c2e554199d49ea9e97726d6bdde83c2019-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08391-yhttps://doaj.org/toc/2041-1723Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system.Sarah GuiziouPauline MayonoveJerome BonnetNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-7 (2019) |
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Science Q |
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Science Q Sarah Guiziou Pauline Mayonove Jerome Bonnet Hierarchical composition of reliable recombinase logic devices |
description |
Genetic logic devices allow the host cell to incorporate multiple inputs to determine output behaviour. Here the authors provide a framework for engineering reliable recombinase-based devices and demonstrate 4-input logic in a multicellular system. |
format |
article |
author |
Sarah Guiziou Pauline Mayonove Jerome Bonnet |
author_facet |
Sarah Guiziou Pauline Mayonove Jerome Bonnet |
author_sort |
Sarah Guiziou |
title |
Hierarchical composition of reliable recombinase logic devices |
title_short |
Hierarchical composition of reliable recombinase logic devices |
title_full |
Hierarchical composition of reliable recombinase logic devices |
title_fullStr |
Hierarchical composition of reliable recombinase logic devices |
title_full_unstemmed |
Hierarchical composition of reliable recombinase logic devices |
title_sort |
hierarchical composition of reliable recombinase logic devices |
publisher |
Nature Portfolio |
publishDate |
2019 |
url |
https://doaj.org/article/63c2e554199d49ea9e97726d6bdde83c |
work_keys_str_mv |
AT sarahguiziou hierarchicalcompositionofreliablerecombinaselogicdevices AT paulinemayonove hierarchicalcompositionofreliablerecombinaselogicdevices AT jeromebonnet hierarchicalcompositionofreliablerecombinaselogicdevices |
_version_ |
1718382448507617280 |