Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of <named-content content-type="genus-species">Neisseria meningitidis</named-content>

Factor H-Dependent Alternative Pathway Inhibition Mediated by Porin B Contributes to Virulence of <named-content content-type="genus-species">Neisseria meningitidis</named-content>

ABSTRACT The identification of “factor H binding protein (fHbp)-null” invasive meningococcal isolates and the realization that widespread use of fHbp-based vaccines could herald selection of such strains prompted us to characterize novel mechanisms of alternative pathway (AP) inhibition on meningoco...

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Autores principales: Lisa A. Lewis, David M. Vu, Shreekant Vasudhev, Jutamas Shaughnessy, Dan M. Granoff, Sanjay Ram
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2013
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/63c632cf777e49d4ba46e0a003471244
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