Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery

Abstract Background The variance in clinical responses to polyetheretherketone (PEEK) cages with titanium (Ti) and hydroxyapatite (HA) coatings (PEEK-Ti-HA cages) is still not clear. In this study, we aimed to evaluate the radiographic and clinical outcomes of patients undergoing TLIF using PEEK-Ti-...

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Autores principales:	Ce Zhu, Miaomiao He, Lili Mao, Huiliang Yang, Bowen Hu, Li Zhang, Ganjun Feng, Limin Liu, Yueming Song
Formato:	article
Lenguaje:	EN
Publicado:	BMC 2021
Materias:	Polyetheretherketone Titanium Hydroxyapatite Cage Transforaminal lumbar interbody fusion Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/63c884e4c8364e81902b611cae263213
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spelling	oai:doaj.org-article:63c884e4c8364e81902b611cae2632132021-11-08T10:58:25ZTitanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery10.1186/s12891-021-04803-71471-2474https://doaj.org/article/63c884e4c8364e81902b611cae2632132021-11-01T00:00:00Zhttps://doi.org/10.1186/s12891-021-04803-7https://doaj.org/toc/1471-2474Abstract Background The variance in clinical responses to polyetheretherketone (PEEK) cages with titanium (Ti) and hydroxyapatite (HA) coatings (PEEK-Ti-HA cages) is still not clear. In this study, we aimed to evaluate the radiographic and clinical outcomes of patients undergoing TLIF using PEEK-Ti-HA cages with a particular focus on fusion rate. Methods A prospective and nonrandomized study was conducted to compare the outcomes of PEEK-Ti-HA cages (group A, n = 32) and uncoated PEEK cages (group B, n = 32). The follow up time was at least 2 years. The radiographic assessments included the regional lordosis (RL), disc height (DH), and fusion rate. The clinical indexes included the Japanese Orthopedic Association (JOA) scores and visual analog scale (VAS) scores (back and leg). Results No significant differences were found in the pre- and postoperative RL and DH between Group A and Group B. And RL and DH, even if there were any variance initially, were restored not long after surgery in both groups. Though Group A had a significantly higher fusion rate than group B at 3 months post-surgery (93.7% vs. 75.0%), the fusion rates for the two groups reached the same level (100%) when it comes to the final follow-up. Additionally, differences of VAS and JOA scores for the two groups in general approximate. Conclusions PEEK-Ti-HA cages, in contrast with uncoated PEEK cages, produced a better fusion rate at 3 months after single-level TLIF. The fusion rates of both groups could get 100% at the final follow-up. PEEK-Ti-HA cages could achieve similar RL, DH, JOA scores and VAS scores in comparison with uncoated PEEK cages post-surgery.Ce ZhuMiaomiao HeLili MaoHuiliang YangBowen HuLi ZhangGanjun FengLimin LiuYueming SongBMCarticlePolyetheretherketoneTitaniumHydroxyapatiteCageTransforaminal lumbar interbody fusionDiseases of the musculoskeletal systemRC925-935ENBMC Musculoskeletal Disorders, Vol 22, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Polyetheretherketone Titanium Hydroxyapatite Cage Transforaminal lumbar interbody fusion Diseases of the musculoskeletal system RC925-935
spellingShingle	Polyetheretherketone Titanium Hydroxyapatite Cage Transforaminal lumbar interbody fusion Diseases of the musculoskeletal system RC925-935 Ce Zhu Miaomiao He Lili Mao Huiliang Yang Bowen Hu Li Zhang Ganjun Feng Limin Liu Yueming Song Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
description	Abstract Background The variance in clinical responses to polyetheretherketone (PEEK) cages with titanium (Ti) and hydroxyapatite (HA) coatings (PEEK-Ti-HA cages) is still not clear. In this study, we aimed to evaluate the radiographic and clinical outcomes of patients undergoing TLIF using PEEK-Ti-HA cages with a particular focus on fusion rate. Methods A prospective and nonrandomized study was conducted to compare the outcomes of PEEK-Ti-HA cages (group A, n = 32) and uncoated PEEK cages (group B, n = 32). The follow up time was at least 2 years. The radiographic assessments included the regional lordosis (RL), disc height (DH), and fusion rate. The clinical indexes included the Japanese Orthopedic Association (JOA) scores and visual analog scale (VAS) scores (back and leg). Results No significant differences were found in the pre- and postoperative RL and DH between Group A and Group B. And RL and DH, even if there were any variance initially, were restored not long after surgery in both groups. Though Group A had a significantly higher fusion rate than group B at 3 months post-surgery (93.7% vs. 75.0%), the fusion rates for the two groups reached the same level (100%) when it comes to the final follow-up. Additionally, differences of VAS and JOA scores for the two groups in general approximate. Conclusions PEEK-Ti-HA cages, in contrast with uncoated PEEK cages, produced a better fusion rate at 3 months after single-level TLIF. The fusion rates of both groups could get 100% at the final follow-up. PEEK-Ti-HA cages could achieve similar RL, DH, JOA scores and VAS scores in comparison with uncoated PEEK cages post-surgery.
format	article
author	Ce Zhu Miaomiao He Lili Mao Huiliang Yang Bowen Hu Li Zhang Ganjun Feng Limin Liu Yueming Song
author_facet	Ce Zhu Miaomiao He Lili Mao Huiliang Yang Bowen Hu Li Zhang Ganjun Feng Limin Liu Yueming Song
author_sort	Ce Zhu
title	Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
title_short	Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
title_full	Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
title_fullStr	Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
title_full_unstemmed	Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
title_sort	titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery
publisher	BMC
publishDate	2021
url	https://doaj.org/article/63c884e4c8364e81902b611cae263213
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Titanium interlayer-mediated hydroxyapatite-coated polyetheretherketone cage in transforaminal lumbar interbody fusion surgery

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