An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides

Protein glycosylation is an essential post-translational modification which analysis is complicated by the diversity of glycan composition and heterogeneity at individual attachment sites. Here the authors describe a method to selectively enrich N-linked glycopeptides to facilitate the detection of...

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Autores principales:	Minyong Chen, Xiaofeng Shi, Rebecca M. Duke, Cristian I. Ruse, Nan Dai, Christopher H. Taron, James C. Samuelson
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/63d113807aad4b368c472143cfecb909
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spelling	oai:doaj.org-article:63d113807aad4b368c472143cfecb9092021-12-02T16:51:47ZAn engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides10.1038/ncomms154872041-1723https://doaj.org/article/63d113807aad4b368c472143cfecb9092017-05-01T00:00:00Zhttps://doi.org/10.1038/ncomms15487https://doaj.org/toc/2041-1723Protein glycosylation is an essential post-translational modification which analysis is complicated by the diversity of glycan composition and heterogeneity at individual attachment sites. Here the authors describe a method to selectively enrich N-linked glycopeptides to facilitate the detection of micro-heterogeneity in N-glycosylation.Minyong ChenXiaofeng ShiRebecca M. DukeCristian I. RuseNan DaiChristopher H. TaronJames C. SamuelsonNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Minyong Chen Xiaofeng Shi Rebecca M. Duke Cristian I. Ruse Nan Dai Christopher H. Taron James C. Samuelson An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
description	Protein glycosylation is an essential post-translational modification which analysis is complicated by the diversity of glycan composition and heterogeneity at individual attachment sites. Here the authors describe a method to selectively enrich N-linked glycopeptides to facilitate the detection of micro-heterogeneity in N-glycosylation.
format	article
author	Minyong Chen Xiaofeng Shi Rebecca M. Duke Cristian I. Ruse Nan Dai Christopher H. Taron James C. Samuelson
author_facet	Minyong Chen Xiaofeng Shi Rebecca M. Duke Cristian I. Ruse Nan Dai Christopher H. Taron James C. Samuelson
author_sort	Minyong Chen
title	An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
title_short	An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
title_full	An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
title_fullStr	An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
title_full_unstemmed	An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides
title_sort	engineered high affinity fbs1 carbohydrate binding protein for selective capture of n-glycans and n-glycopeptides
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/63d113807aad4b368c472143cfecb909
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An engineered high affinity Fbs1 carbohydrate binding protein for selective capture of N-glycans and N-glycopeptides

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