Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia

Flavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli1 1Department of Medicine and Surgery, University of Salerno, Salerno, Italy; 2Department of Ophthalmology, A.O.U. San Giovanni Di Dio e Ruggi d’Aragona-Scuola Medica Salernitana, Salerno, Italy; 3Division of Op...

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Autores principales:	Gallo FG, Plaitano C, Esposito Veneruso P, Magli A
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	strabismus pediatric congenital Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/63d43c5490274b27b68801fade428203
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spelling	oai:doaj.org-article:63d43c5490274b27b68801fade4282032021-12-02T11:07:48ZLong-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia1177-5483https://doaj.org/article/63d43c5490274b27b68801fade4282032020-10-01T00:00:00Zhttps://test.dovepress.com/long-term-effects-of-botulinum-toxin-in-large-angle-infantile-esotropi-peer-reviewed-article-OPTHhttps://doaj.org/toc/1177-5483Flavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli1 1Department of Medicine and Surgery, University of Salerno, Salerno, Italy; 2Department of Ophthalmology, A.O.U. San Giovanni Di Dio e Ruggi d’Aragona-Scuola Medica Salernitana, Salerno, Italy; 3Division of Ophthalmology, University Hospital “Federico II”, Naples, ItalyCorrespondence: Flavio Gioele GalloDepartment of Medicine and Surgery, University of Salerno, Via Salvador Allende, 43, Baronissi, Salerno 84081, ItalyTel +39 3898535899Email gallo.flavio.gioele@gmail.comPurpose: The purpose of this study is the motor outcome analysis of early Botulinum toxin (BT) treatment in patients affected by large-angle infantile esotropia (IE).Patients and Methods: Retrospective analysis of 130 medical charts of IE patients who underwent BT injections between 2004 and 2019 was performed. All patients underwent BT injections within 13 months of age.Results: Thirty patients, matching the inclusion criteria, were included in the study. Twenty-eight patients showing residual ET ≥ 25 PD (34.3± 6.6 PD ranged from 25 to 50) underwent surgery.Conclusion: Our result after 1 Botulinum toxin injection showed a very low success rate (6.7%) at last follow-up (28.3± 7.2 months). Our data would suggest one Botulinum toxin injection in children affected by large-angle infantile esotropia allows a significant reduction of deviation but does not avoid the need for surgical treatment.Keywords: strabismus, pediatric, congenitalGallo FGPlaitano CEsposito Veneruso PMagli ADove Medical PressarticlestrabismuspediatriccongenitalOphthalmologyRE1-994ENClinical Ophthalmology, Vol Volume 14, Pp 3399-3402 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	strabismus pediatric congenital Ophthalmology RE1-994
spellingShingle	strabismus pediatric congenital Ophthalmology RE1-994 Gallo FG Plaitano C Esposito Veneruso P Magli A Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
description	Flavio Gioele Gallo,1 Carmen Plaitano,2 Paolo Esposito Veneruso,3 Adriano Magli1 1Department of Medicine and Surgery, University of Salerno, Salerno, Italy; 2Department of Ophthalmology, A.O.U. San Giovanni Di Dio e Ruggi d’Aragona-Scuola Medica Salernitana, Salerno, Italy; 3Division of Ophthalmology, University Hospital “Federico II”, Naples, ItalyCorrespondence: Flavio Gioele GalloDepartment of Medicine and Surgery, University of Salerno, Via Salvador Allende, 43, Baronissi, Salerno 84081, ItalyTel +39 3898535899Email gallo.flavio.gioele@gmail.comPurpose: The purpose of this study is the motor outcome analysis of early Botulinum toxin (BT) treatment in patients affected by large-angle infantile esotropia (IE).Patients and Methods: Retrospective analysis of 130 medical charts of IE patients who underwent BT injections between 2004 and 2019 was performed. All patients underwent BT injections within 13 months of age.Results: Thirty patients, matching the inclusion criteria, were included in the study. Twenty-eight patients showing residual ET ≥ 25 PD (34.3± 6.6 PD ranged from 25 to 50) underwent surgery.Conclusion: Our result after 1 Botulinum toxin injection showed a very low success rate (6.7%) at last follow-up (28.3± 7.2 months). Our data would suggest one Botulinum toxin injection in children affected by large-angle infantile esotropia allows a significant reduction of deviation but does not avoid the need for surgical treatment.Keywords: strabismus, pediatric, congenital
format	article
author	Gallo FG Plaitano C Esposito Veneruso P Magli A
author_facet	Gallo FG Plaitano C Esposito Veneruso P Magli A
author_sort	Gallo FG
title	Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
title_short	Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
title_full	Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
title_fullStr	Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
title_full_unstemmed	Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia
title_sort	long-term effects of botulinum toxin in large-angle infantile esotropia
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/63d43c5490274b27b68801fade428203
work_keys_str_mv	AT gallofg longtermeffectsofbotulinumtoxininlargeangleinfantileesotropia AT plaitanoc longtermeffectsofbotulinumtoxininlargeangleinfantileesotropia AT espositovenerusop longtermeffectsofbotulinumtoxininlargeangleinfantileesotropia AT maglia longtermeffectsofbotulinumtoxininlargeangleinfantileesotropia
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Long-Term Effects of Botulinum Toxin in Large-Angle Infantile Esotropia

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