Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection

ABSTRACT: Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic a...

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Autores principales:	Breno Lima de Almeida, Marta Giovanetti, João Vitor Oliveira, Tereza Cristina Xavier Carvalho, Eduardo Manoel Figueiredo, Rosana Pellegrini, Juan Ignacio Calcagno, Marcia Weber Carneiro, Juliana M.G.C. de Oliveira, Adriana Virgínia Barros Faiçal, Iluska Andrade Agra, Cristina Salles, Emília Katiane Embiruçu de Araújo Leão, Rita Lucena, Angelina X. Acosta, Luiz Carlos Junior Alcantara, Isadora Cristina de Siqueira
Formato:	article
Lenguaje:	EN
Publicado:	Elsevier 2022
Materias:	Zika virus Congenital infection Viral sequencing Phylogenetic analysis Infectious and parasitic diseases RC109-216
Acceso en línea:	https://doaj.org/article/63d6607ad24b45ab8d9bec12ed47bc0f
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spelling	oai:doaj.org-article:63d6607ad24b45ab8d9bec12ed47bc0f2021-11-30T04:14:28ZDetection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection1201-971210.1016/j.ijid.2021.10.051https://doaj.org/article/63d6607ad24b45ab8d9bec12ed47bc0f2022-01-01T00:00:00Zhttp://www.sciencedirect.com/science/article/pii/S1201971221008419https://doaj.org/toc/1201-9712ABSTRACT: Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.Breno Lima de AlmeidaMarta GiovanettiJoão Vitor OliveiraTereza Cristina Xavier CarvalhoEduardo Manoel FigueiredoRosana PellegriniJuan Ignacio CalcagnoMarcia Weber CarneiroJuliana M.G.C. de OliveiraAdriana Virgínia Barros FaiçalIluska Andrade AgraCristina SallesEmília Katiane Embiruçu de Araújo LeãoRita LucenaAngelina X. AcostaLuiz Carlos Junior AlcantaraIsadora Cristina de SiqueiraElsevierarticleZika virusCongenital infectionViral sequencingPhylogenetic analysisInfectious and parasitic diseasesRC109-216ENInternational Journal of Infectious Diseases, Vol 114, Iss , Pp 128-131 (2022)
institution	DOAJ
collection	DOAJ
language	EN
topic	Zika virus Congenital infection Viral sequencing Phylogenetic analysis Infectious and parasitic diseases RC109-216
spellingShingle	Zika virus Congenital infection Viral sequencing Phylogenetic analysis Infectious and parasitic diseases RC109-216 Breno Lima de Almeida Marta Giovanetti João Vitor Oliveira Tereza Cristina Xavier Carvalho Eduardo Manoel Figueiredo Rosana Pellegrini Juan Ignacio Calcagno Marcia Weber Carneiro Juliana M.G.C. de Oliveira Adriana Virgínia Barros Faiçal Iluska Andrade Agra Cristina Salles Emília Katiane Embiruçu de Araújo Leão Rita Lucena Angelina X. Acosta Luiz Carlos Junior Alcantara Isadora Cristina de Siqueira Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
description	ABSTRACT: Fourteen asymptomatic normocephalic newborns with confirmed congenital Zika infection were investigated. All newborns presented Zika virus (ZIKV) positivity on reverse transcriptase polymerase chain reaction. Following ZIKV-specific NS5 gene fragment sequencing in one child, phylogenetic analysis revealed that this isolate belonged to the Asian genotype, and clustered closely with other sequences previously isolated in north-east and northern regions of Brazil.
format	article
author	Breno Lima de Almeida Marta Giovanetti João Vitor Oliveira Tereza Cristina Xavier Carvalho Eduardo Manoel Figueiredo Rosana Pellegrini Juan Ignacio Calcagno Marcia Weber Carneiro Juliana M.G.C. de Oliveira Adriana Virgínia Barros Faiçal Iluska Andrade Agra Cristina Salles Emília Katiane Embiruçu de Araújo Leão Rita Lucena Angelina X. Acosta Luiz Carlos Junior Alcantara Isadora Cristina de Siqueira
author_facet	Breno Lima de Almeida Marta Giovanetti João Vitor Oliveira Tereza Cristina Xavier Carvalho Eduardo Manoel Figueiredo Rosana Pellegrini Juan Ignacio Calcagno Marcia Weber Carneiro Juliana M.G.C. de Oliveira Adriana Virgínia Barros Faiçal Iluska Andrade Agra Cristina Salles Emília Katiane Embiruçu de Araújo Leão Rita Lucena Angelina X. Acosta Luiz Carlos Junior Alcantara Isadora Cristina de Siqueira
author_sort	Breno Lima de Almeida
title	Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
title_short	Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
title_full	Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
title_fullStr	Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
title_full_unstemmed	Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection
title_sort	detection and sequencing of zika virus in normocephalic newborns with congenital zika infection
publisher	Elsevier
publishDate	2022
url	https://doaj.org/article/63d6607ad24b45ab8d9bec12ed47bc0f
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Detection and sequencing of Zika virus in normocephalic newborns with congenital Zika infection

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