ROM Plus®: accurate point-of-care detection of ruptured fetal membranes

Ross W McQuivey,1 Jon E Block2 1Clinical Affairs, Clinical Innovations, Salt Lake City, UT, 2Independent Clinical Consultant, San Francisco, CA, USAAbstract: Accurate and timely diagnosis of rupture of fetal membranes is imperative to inform and guide gestational age-specific interventions to optimi...

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Autores principales: McQuivey RW, Block JE
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2016
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Acceso en línea:https://doaj.org/article/63d7f04434db475491f26bcba380be9e
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spelling oai:doaj.org-article:63d7f04434db475491f26bcba380be9e2021-12-02T00:53:44ZROM Plus®: accurate point-of-care detection of ruptured fetal membranes1179-1470https://doaj.org/article/63d7f04434db475491f26bcba380be9e2016-05-01T00:00:00Zhttps://www.dovepress.com/rom-plusreg-accurate-point-of-care-detection-of-ruptured-fetal-membran-peer-reviewed-article-MDERhttps://doaj.org/toc/1179-1470Ross W McQuivey,1 Jon E Block2 1Clinical Affairs, Clinical Innovations, Salt Lake City, UT, 2Independent Clinical Consultant, San Francisco, CA, USAAbstract: Accurate and timely diagnosis of rupture of fetal membranes is imperative to inform and guide gestational age-specific interventions to optimize perinatal outcomes and reduce the risk of serious complications, including preterm delivery and infections. The ROM Plus is a rapid, point-of-care, qualitative immunochromatographic diagnostic test that uses a unique monoclonal/polyclonal antibody approach to detect two different proteins found in amniotic fluid at high concentrations: alpha-fetoprotein and insulin-like growth factor binding protein-1. Clinical study results have uniformly demonstrated high diagnostic accuracy and performance characteristics with this point-of-care test that exceeds conventional clinical testing with external laboratory evaluation. The description, indications for use, procedural steps, and laboratory and clinical characterization of this assay are presented in this article.Keywords: ROM Plus®, premature rupture of membranes, point-of-care immunoassay, insulin-like growth factor binding protein-1, IGFBP-1, placental protein 12, PP12, alpha-fetoprotein, AFPMcQuivey RWBlock JEDove Medical PressarticleKeywords: ROM Plus®premature rupture of membranespoint of care immunoassayplacental protein 12 (PP12)alpha-fetoprotein (AFP)Medical technologyR855-855.5ENMedical Devices: Evidence and Research, Vol 2016, Iss Issue 1, Pp 69-74 (2016)
institution DOAJ
collection DOAJ
language EN
topic Keywords: ROM Plus®
premature rupture of membranes
point of care immunoassay
placental protein 12 (PP12)
alpha-fetoprotein (AFP)
Medical technology
R855-855.5
spellingShingle Keywords: ROM Plus®
premature rupture of membranes
point of care immunoassay
placental protein 12 (PP12)
alpha-fetoprotein (AFP)
Medical technology
R855-855.5
McQuivey RW
Block JE
ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
description Ross W McQuivey,1 Jon E Block2 1Clinical Affairs, Clinical Innovations, Salt Lake City, UT, 2Independent Clinical Consultant, San Francisco, CA, USAAbstract: Accurate and timely diagnosis of rupture of fetal membranes is imperative to inform and guide gestational age-specific interventions to optimize perinatal outcomes and reduce the risk of serious complications, including preterm delivery and infections. The ROM Plus is a rapid, point-of-care, qualitative immunochromatographic diagnostic test that uses a unique monoclonal/polyclonal antibody approach to detect two different proteins found in amniotic fluid at high concentrations: alpha-fetoprotein and insulin-like growth factor binding protein-1. Clinical study results have uniformly demonstrated high diagnostic accuracy and performance characteristics with this point-of-care test that exceeds conventional clinical testing with external laboratory evaluation. The description, indications for use, procedural steps, and laboratory and clinical characterization of this assay are presented in this article.Keywords: ROM Plus®, premature rupture of membranes, point-of-care immunoassay, insulin-like growth factor binding protein-1, IGFBP-1, placental protein 12, PP12, alpha-fetoprotein, AFP
format article
author McQuivey RW
Block JE
author_facet McQuivey RW
Block JE
author_sort McQuivey RW
title ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
title_short ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
title_full ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
title_fullStr ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
title_full_unstemmed ROM Plus®: accurate point-of-care detection of ruptured fetal membranes
title_sort rom plus®: accurate point-of-care detection of ruptured fetal membranes
publisher Dove Medical Press
publishDate 2016
url https://doaj.org/article/63d7f04434db475491f26bcba380be9e
work_keys_str_mv AT mcquiveyrw romplusregaccuratepointofcaredetectionofrupturedfetalmembranes
AT blockje romplusregaccuratepointofcaredetectionofrupturedfetalmembranes
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