Regulation of innate immune responses in macrophages differentiated in the presence of vitamin D and infected with dengue virus 2.
A dysregulated or exacerbated inflammatory response is thought to be the key driver of the pathogenesis of severe disease caused by the mosquito-borne dengue virus (DENV). Compounds that restrict virus replication and modulate the inflammatory response could thus serve as promising therapeutics miti...
Guardado en:
Autores principales: | Jorge Andrés Castillo, Diana M Giraldo, Juan C Hernandez, Jolanda M Smit, Izabela A Rodenhuis-Zybert, Silvio Urcuqui-Inchima |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/63db230099ec4adf8a56a23c23246927 |
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