Differential p53-Mediated Cellular Responses to DNA-Damaging Therapeutic Agents
The gene <i>TP53</i>, which encodes the tumor suppressor protein p53, is mutated in about 50% of cancers. In response to cell stressors like DNA damage and after treatment with DNA-damaging therapeutic agents, p53 acts as a transcription factor to activate subsets of target genes which c...
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| Autores principales: | , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
MDPI AG
2021
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| Acceso en línea: | https://doaj.org/article/63e53515f0ec4079b1faa8341d961d21 |
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