Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence

The role of human CD4+ T cell subsets in cancer immunotherapy is still unclear. Here, the authors show that CD26 identifies three CD4+ T cell subsets with distinct immunological properties in both healthy individuals and cancer patients.

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Autores principales: Stefanie R. Bailey, Michelle H. Nelson, Kinga Majchrzak, Jacob S. Bowers, Megan M. Wyatt, Aubrey S. Smith, Lillian R. Neal, Keisuke Shirai, Carmine Carpenito, Carl H. June, Michael J. Zilliox, Chrystal M. Paulos
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/63f1a5f94c67463f9202a2a71250b8b7
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spelling oai:doaj.org-article:63f1a5f94c67463f9202a2a71250b8b72021-12-02T14:41:59ZHuman CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence10.1038/s41467-017-01867-92041-1723https://doaj.org/article/63f1a5f94c67463f9202a2a71250b8b72017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01867-9https://doaj.org/toc/2041-1723The role of human CD4+ T cell subsets in cancer immunotherapy is still unclear. Here, the authors show that CD26 identifies three CD4+ T cell subsets with distinct immunological properties in both healthy individuals and cancer patients.Stefanie R. BaileyMichelle H. NelsonKinga MajchrzakJacob S. BowersMegan M. WyattAubrey S. SmithLillian R. NealKeisuke ShiraiCarmine CarpenitoCarl H. JuneMichael J. ZillioxChrystal M. PaulosNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Stefanie R. Bailey
Michelle H. Nelson
Kinga Majchrzak
Jacob S. Bowers
Megan M. Wyatt
Aubrey S. Smith
Lillian R. Neal
Keisuke Shirai
Carmine Carpenito
Carl H. June
Michael J. Zilliox
Chrystal M. Paulos
Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
description The role of human CD4+ T cell subsets in cancer immunotherapy is still unclear. Here, the authors show that CD26 identifies three CD4+ T cell subsets with distinct immunological properties in both healthy individuals and cancer patients.
format article
author Stefanie R. Bailey
Michelle H. Nelson
Kinga Majchrzak
Jacob S. Bowers
Megan M. Wyatt
Aubrey S. Smith
Lillian R. Neal
Keisuke Shirai
Carmine Carpenito
Carl H. June
Michael J. Zilliox
Chrystal M. Paulos
author_facet Stefanie R. Bailey
Michelle H. Nelson
Kinga Majchrzak
Jacob S. Bowers
Megan M. Wyatt
Aubrey S. Smith
Lillian R. Neal
Keisuke Shirai
Carmine Carpenito
Carl H. June
Michael J. Zilliox
Chrystal M. Paulos
author_sort Stefanie R. Bailey
title Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
title_short Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
title_full Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
title_fullStr Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
title_full_unstemmed Human CD26high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
title_sort human cd26high t cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/63f1a5f94c67463f9202a2a71250b8b7
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