Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).

A living-donor kidney transplant (LDKT) is one of the best treatments for kidney failure. The UK's LDKT activity falls behind that of many other countries, and there is evidence of socioeconomic inequity in access. We aimed to develop a UK-specific multicomponent intervention to support eligibl...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Pippa K Bailey, Yoav Ben-Shlomo, Fergus J Caskey, Mohammed Al-Talib, Hannah Lyons, Adarsh Babu, Liise K Kayler, Lucy E Selman
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/63f41cc27b134e098ba03cddf57c2701
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:63f41cc27b134e098ba03cddf57c2701
record_format	dspace
spelling	oai:doaj.org-article:63f41cc27b134e098ba03cddf57c27012021-12-02T20:09:59ZDevelopment of an intervention to improve access to living-donor kidney transplantation (the ASK study).1932-620310.1371/journal.pone.0253667https://doaj.org/article/63f41cc27b134e098ba03cddf57c27012021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0253667https://doaj.org/toc/1932-6203A living-donor kidney transplant (LDKT) is one of the best treatments for kidney failure. The UK's LDKT activity falls behind that of many other countries, and there is evidence of socioeconomic inequity in access. We aimed to develop a UK-specific multicomponent intervention to support eligible individuals to access a LDKT. The intervention was designed to support those who are socioeconomically-deprived and currently disadvantaged, by targeting mediators of inequity identified in earlier work. We identified three existing interventions in the literature which target these mediators: a) the Norway model (healthcare practitioners contact patients' family with information about kidney donation), b) a home education model, and c) a Transplant candidate advocate model. We undertook intervention development using the Person-Based Approach (PBA). We performed in-depth qualitative interviews with people with advanced kidney disease (n = 13), their family members (n = 4), and renal and transplant healthcare practitioners (n = 15), analysed using thematic analysis. We investigated participant views on each proposed intervention component. We drafted intervention resources and revised these in light of comments from qualitative 'think-aloud' interviews. Four general themes were identified: i) Perceived cultural and societal norms; ii) Influence of family on decision-making; iii) Resource limitation, and iv) Evidence of effectiveness. For each intervention discussed, we identified three themes: for the Norway model: i) Overcoming communication barriers and assumptions; ii) Request from an official third party, and iii) Risk of coercion; for the home education model: i) Intragroup dynamics; ii) Avoidance of hospital, and iii) Burdens on participants; and for the transplant candidate advocates model: i) Vested interest of advocates; ii) Time commitment, and iii) Risk of misinformation. We used these results to develop a multicomponent intervention which comprises components from existing interventions that have been adapted to increase acceptability and engagement in a UK population. This will be evaluated in a future randomised controlled trial.Pippa K BaileyYoav Ben-ShlomoFergus J CaskeyMohammed Al-TalibHannah LyonsAdarsh BabuLiise K KaylerLucy E SelmanPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 6, p e0253667 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Pippa K Bailey Yoav Ben-Shlomo Fergus J Caskey Mohammed Al-Talib Hannah Lyons Adarsh Babu Liise K Kayler Lucy E Selman Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
description	A living-donor kidney transplant (LDKT) is one of the best treatments for kidney failure. The UK's LDKT activity falls behind that of many other countries, and there is evidence of socioeconomic inequity in access. We aimed to develop a UK-specific multicomponent intervention to support eligible individuals to access a LDKT. The intervention was designed to support those who are socioeconomically-deprived and currently disadvantaged, by targeting mediators of inequity identified in earlier work. We identified three existing interventions in the literature which target these mediators: a) the Norway model (healthcare practitioners contact patients' family with information about kidney donation), b) a home education model, and c) a Transplant candidate advocate model. We undertook intervention development using the Person-Based Approach (PBA). We performed in-depth qualitative interviews with people with advanced kidney disease (n = 13), their family members (n = 4), and renal and transplant healthcare practitioners (n = 15), analysed using thematic analysis. We investigated participant views on each proposed intervention component. We drafted intervention resources and revised these in light of comments from qualitative 'think-aloud' interviews. Four general themes were identified: i) Perceived cultural and societal norms; ii) Influence of family on decision-making; iii) Resource limitation, and iv) Evidence of effectiveness. For each intervention discussed, we identified three themes: for the Norway model: i) Overcoming communication barriers and assumptions; ii) Request from an official third party, and iii) Risk of coercion; for the home education model: i) Intragroup dynamics; ii) Avoidance of hospital, and iii) Burdens on participants; and for the transplant candidate advocates model: i) Vested interest of advocates; ii) Time commitment, and iii) Risk of misinformation. We used these results to develop a multicomponent intervention which comprises components from existing interventions that have been adapted to increase acceptability and engagement in a UK population. This will be evaluated in a future randomised controlled trial.
format	article
author	Pippa K Bailey Yoav Ben-Shlomo Fergus J Caskey Mohammed Al-Talib Hannah Lyons Adarsh Babu Liise K Kayler Lucy E Selman
author_facet	Pippa K Bailey Yoav Ben-Shlomo Fergus J Caskey Mohammed Al-Talib Hannah Lyons Adarsh Babu Liise K Kayler Lucy E Selman
author_sort	Pippa K Bailey
title	Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
title_short	Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
title_full	Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
title_fullStr	Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
title_full_unstemmed	Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).
title_sort	development of an intervention to improve access to living-donor kidney transplantation (the ask study).
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/63f41cc27b134e098ba03cddf57c2701
work_keys_str_mv	AT pippakbailey developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT yoavbenshlomo developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT fergusjcaskey developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT mohammedaltalib developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT hannahlyons developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT adarshbabu developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT liisekkayler developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy AT lucyeselman developmentofaninterventiontoimproveaccesstolivingdonorkidneytransplantationtheaskstudy
_version_	1718375064997462016

Development of an intervention to improve access to living-donor kidney transplantation (the ASK study).

Ejemplares similares