Transdermal delivery of nobiletin using ionic liquids
Abstract Nobiletin (NOB), a flavonoid, has extremely low water solubility and low oral bioavailability; however, despite these problems, various physiological effects have been investigated in vitro. In the present study, we investigated the transdermal delivery of NOB using choline and geranic acid...
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Autores principales: | Tadashi Hattori, Hiroki Tagawa, Makoto Inai, Toshiyuki Kan, Shin-ichiro Kimura, Shigeru Itai, Samir Mitragotri, Yasunori Iwao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/63fa0dea7c1444fd9daa6d6a0abd59dc |
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