Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides

The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an unsolved problem despite their significant synthetic potential. Here, the authors show that alkyl chlorides can efficiently participate in Mizoroki–Heck cross-coupling reactions with excellent functional group com...

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Autores principales:	Geun Seok Lee, Daeun Kim, Soon Hyeok Hong
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/63fbe0bfb95a4d80b7a6b40ed0b1d0dc
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spelling	oai:doaj.org-article:63fbe0bfb95a4d80b7a6b40ed0b1d0dc2021-12-02T14:11:08ZPd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides10.1038/s41467-021-21270-92041-1723https://doaj.org/article/63fbe0bfb95a4d80b7a6b40ed0b1d0dc2021-02-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-21270-9https://doaj.org/toc/2041-1723The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an unsolved problem despite their significant synthetic potential. Here, the authors show that alkyl chlorides can efficiently participate in Mizoroki–Heck cross-coupling reactions with excellent functional group compatibility via photoinduced Pd catalysis.Geun Seok LeeDaeun KimSoon Hyeok HongNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Geun Seok Lee Daeun Kim Soon Hyeok Hong Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
description	The use of alkyl chlorides in Pd-catalyzed Mizoroki–Heck coupling reactions remains an unsolved problem despite their significant synthetic potential. Here, the authors show that alkyl chlorides can efficiently participate in Mizoroki–Heck cross-coupling reactions with excellent functional group compatibility via photoinduced Pd catalysis.
format	article
author	Geun Seok Lee Daeun Kim Soon Hyeok Hong
author_facet	Geun Seok Lee Daeun Kim Soon Hyeok Hong
author_sort	Geun Seok Lee
title	Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
title_short	Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
title_full	Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
title_fullStr	Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
title_full_unstemmed	Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides
title_sort	pd-catalyzed formal mizoroki–heck coupling of unactivated alkyl chlorides
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/63fbe0bfb95a4d80b7a6b40ed0b1d0dc
work_keys_str_mv	AT geunseoklee pdcatalyzedformalmizorokiheckcouplingofunactivatedalkylchlorides AT daeunkim pdcatalyzedformalmizorokiheckcouplingofunactivatedalkylchlorides AT soonhyeokhong pdcatalyzedformalmizorokiheckcouplingofunactivatedalkylchlorides
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Pd-catalyzed formal Mizoroki–Heck coupling of unactivated alkyl chlorides

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