A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions

The development of neonatal necrotising enterocolitis has been temporally associated with red blood cell transfusions in retrospective human studies. Here, the authors develop a neonatal mouse model of necrotising enterocolitis in anaemic mice receiving red blood cell transfusion that recapitulates...

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Autores principales: Krishnan MohanKumar, Kopperuncholan Namachivayam, Tanjing Song, Byeong Jake Cha, Andrea Slate, Jeanne E. Hendrickson, Hua Pan, Samuel A. Wickline, Joo-Yeun Oh, Rakesh P. Patel, Ling He, Benjamin A. Torres, Akhil Maheshwari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/6410e0e9afc14c3486229368579878f2
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Sumario:The development of neonatal necrotising enterocolitis has been temporally associated with red blood cell transfusions in retrospective human studies. Here, the authors develop a neonatal mouse model of necrotising enterocolitis in anaemic mice receiving red blood cell transfusion that recapitulates features of the human condition.