Insufficient transparency of statistical reporting in preclinical research: a scoping review

Abstract Non-transparent statistical reporting contributes to the reproducibility crisis in life sciences, despite guidelines and educational articles regularly published. Envisioning more effective measures for ensuring transparency requires the detailed monitoring of incomplete reporting in the li...

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Autor principal:	Romain-Daniel Gosselin
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6410ffcf528242e891b0d44b0988c5b0
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spelling	oai:doaj.org-article:6410ffcf528242e891b0d44b0988c5b02021-12-02T13:30:27ZInsufficient transparency of statistical reporting in preclinical research: a scoping review10.1038/s41598-021-83006-52045-2322https://doaj.org/article/6410ffcf528242e891b0d44b0988c5b02021-02-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-83006-5https://doaj.org/toc/2045-2322Abstract Non-transparent statistical reporting contributes to the reproducibility crisis in life sciences, despite guidelines and educational articles regularly published. Envisioning more effective measures for ensuring transparency requires the detailed monitoring of incomplete reporting in the literature. In this study, a systematic approach was used to sample 16 periodicals from the ISI Journal Citation Report database and to collect 233 preclinical articles (including both in vitro and animal research) from online journal content published in 2019. Statistical items related to the use of location tests were quantified. Results revealed that a large proportion of articles insufficiently describe tests (median 44.8%, IQR [33.3–62.5%], k = 16 journals), software (31%, IQR [22.3–39.6%]) or sample sizes (44.2%, IQR [35.7–55.4%]). The results further point at contradictory information as a component of poor reporting (18.3%, IQR [6.79–26.7%]). No detectable correlation was found between journal impact factor and the quality of statistical reporting of any studied item. The under-representation of open-source software (4.50% of articles) suggests that the provision of code should remain restricted to articles that use such packages. Since mounting evidence indicates that transparency is key for reproducible science, this work highlights the need for a more rigorous enforcement of existing guidelines.Romain-Daniel GosselinNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Romain-Daniel Gosselin Insufficient transparency of statistical reporting in preclinical research: a scoping review
description	Abstract Non-transparent statistical reporting contributes to the reproducibility crisis in life sciences, despite guidelines and educational articles regularly published. Envisioning more effective measures for ensuring transparency requires the detailed monitoring of incomplete reporting in the literature. In this study, a systematic approach was used to sample 16 periodicals from the ISI Journal Citation Report database and to collect 233 preclinical articles (including both in vitro and animal research) from online journal content published in 2019. Statistical items related to the use of location tests were quantified. Results revealed that a large proportion of articles insufficiently describe tests (median 44.8%, IQR [33.3–62.5%], k = 16 journals), software (31%, IQR [22.3–39.6%]) or sample sizes (44.2%, IQR [35.7–55.4%]). The results further point at contradictory information as a component of poor reporting (18.3%, IQR [6.79–26.7%]). No detectable correlation was found between journal impact factor and the quality of statistical reporting of any studied item. The under-representation of open-source software (4.50% of articles) suggests that the provision of code should remain restricted to articles that use such packages. Since mounting evidence indicates that transparency is key for reproducible science, this work highlights the need for a more rigorous enforcement of existing guidelines.
format	article
author	Romain-Daniel Gosselin
author_facet	Romain-Daniel Gosselin
author_sort	Romain-Daniel Gosselin
title	Insufficient transparency of statistical reporting in preclinical research: a scoping review
title_short	Insufficient transparency of statistical reporting in preclinical research: a scoping review
title_full	Insufficient transparency of statistical reporting in preclinical research: a scoping review
title_fullStr	Insufficient transparency of statistical reporting in preclinical research: a scoping review
title_full_unstemmed	Insufficient transparency of statistical reporting in preclinical research: a scoping review
title_sort	insufficient transparency of statistical reporting in preclinical research: a scoping review
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/6410ffcf528242e891b0d44b0988c5b0
work_keys_str_mv	AT romaindanielgosselin insufficienttransparencyofstatisticalreportinginpreclinicalresearchascopingreview
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Insufficient transparency of statistical reporting in preclinical research: a scoping review

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