Whole-genome sequencing analysis of the cardiometabolic proteome

Whole-genome sequencing analysis of the cardiometabolic proteome

The human proteome represents a crucial link between complex disease and genetic/environmental factors. Here, the authors investigate 257 cardiometabolic-relevant protein biomarkers in whole genome sequencing data from 1328 individuals, revealing the genetic architecture underlying biomarker variati...

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Autores principales: Arthur Gilly, Young-Chan Park, Grace Png, Andrei Barysenka, Iris Fischer, Thea Bjørnland, Lorraine Southam, Daniel Suveges, Sonja Neumeyer, N. William Rayner, Emmanouil Tsafantakis, Maria Karaleftheri, George Dedoussis, Eleftheria Zeggini
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Q
Acceso en línea:https://doaj.org/article/641fcf7725ae4b8ab2f58f76c9c92e4f
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spelling oai:doaj.org-article:641fcf7725ae4b8ab2f58f76c9c92e4f2021-12-02T14:16:40ZWhole-genome sequencing analysis of the cardiometabolic proteome10.1038/s41467-020-20079-22041-1723https://doaj.org/article/641fcf7725ae4b8ab2f58f76c9c92e4f2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20079-2https://doaj.org/toc/2041-1723The human proteome represents a crucial link between complex disease and genetic/environmental factors. Here, the authors investigate 257 cardiometabolic-relevant protein biomarkers in whole genome sequencing data from 1328 individuals, revealing the genetic architecture underlying biomarker variation.Arthur GillyYoung-Chan ParkGrace PngAndrei BarysenkaIris FischerThea BjørnlandLorraine SouthamDaniel SuvegesSonja NeumeyerN. William RaynerEmmanouil TsafantakisMaria KaraleftheriGeorge DedoussisEleftheria ZegginiNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Arthur Gilly
Young-Chan Park
Grace Png
Andrei Barysenka
Iris Fischer
Thea Bjørnland
Lorraine Southam
Daniel Suveges
Sonja Neumeyer
N. William Rayner
Emmanouil Tsafantakis
Maria Karaleftheri
George Dedoussis
Eleftheria Zeggini
Whole-genome sequencing analysis of the cardiometabolic proteome
description The human proteome represents a crucial link between complex disease and genetic/environmental factors. Here, the authors investigate 257 cardiometabolic-relevant protein biomarkers in whole genome sequencing data from 1328 individuals, revealing the genetic architecture underlying biomarker variation.
format article
author Arthur Gilly
Young-Chan Park
Grace Png
Andrei Barysenka
Iris Fischer
Thea Bjørnland
Lorraine Southam
Daniel Suveges
Sonja Neumeyer
N. William Rayner
Emmanouil Tsafantakis
Maria Karaleftheri
George Dedoussis
Eleftheria Zeggini
author_facet Arthur Gilly
Young-Chan Park
Grace Png
Andrei Barysenka
Iris Fischer
Thea Bjørnland
Lorraine Southam
Daniel Suveges
Sonja Neumeyer
N. William Rayner
Emmanouil Tsafantakis
Maria Karaleftheri
George Dedoussis
Eleftheria Zeggini
author_sort Arthur Gilly
title Whole-genome sequencing analysis of the cardiometabolic proteome
title_short Whole-genome sequencing analysis of the cardiometabolic proteome
title_full Whole-genome sequencing analysis of the cardiometabolic proteome
title_fullStr Whole-genome sequencing analysis of the cardiometabolic proteome
title_full_unstemmed Whole-genome sequencing analysis of the cardiometabolic proteome
title_sort whole-genome sequencing analysis of the cardiometabolic proteome
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/641fcf7725ae4b8ab2f58f76c9c92e4f
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