Systemic nanoparticle delivery of CRISPR-Cas9 ribonucleoproteins for effective tissue specific genome editing
Therapeutic targets of CRISPR-Cas can often not be accessed due to lack of carriers to deliver RNPs systematically. Here, the authors engineer modified lipid nanoparticles for delivery of gene editing proteins to specific tissues.
Guardado en:
Autores principales: | Tuo Wei, Qiang Cheng, Yi-Li Min, Eric N. Olson, Daniel J. Siegwart |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/643f6e049bbd4fa2a9c4925cf329f370 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Genome editing in maize directed by CRISPR–Cas9 ribonucleoprotein complexes
por: Sergei Svitashev, et al.
Publicado: (2016) -
Targeted delivery of CRISPR-Cas9 ribonucleoprotein into arthropod ovaries for heritable germline gene editing
por: Duverney Chaverra-Rodriguez, et al.
Publicado: (2018) -
Efficient DNA-free genome editing of bread wheat using CRISPR/Cas9 ribonucleoprotein complexes
por: Zhen Liang, et al.
Publicado: (2017) -
Rapid, Selection-Free, High-Efficiency Genome Editing in Protozoan Parasites Using CRISPR-Cas9 Ribonucleoproteins
por: Lia Carolina Soares Medeiros, et al.
Publicado: (2017) -
Development of a pVEC peptide-based ribonucleoprotein (RNP) delivery system for genome editing using CRISPR/Cas9 in Chlamydomonas reinhardtii
por: Seongsu Kang, et al.
Publicado: (2020)