Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Surface modification of pig endothelial cells with a branched heparin conjugate improves their compatibility with human blood

Abstract Corline Heparin Conjugate (CHC), a compound of multiple unfractionated heparin chains, coats cells with a glycocalyx-like layer and may inhibit (xeno)transplant-associated activation of the plasma cascade systems. Here, we investigated the use of CHC to protect WT and genetically modified (...

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Autores principales: Anjan K. Bongoni, Evelyn Salvaris, Sofia Nordling, Nikolai Klymiuk, Eckhard Wolf, David L. Ayares, Robert Rieben, Peetra U. Magnusson, Peter J. Cowan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/644500d90d4649d2a075e77455a6fe32
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