EXPERIENCE IN LOCAL IMMUNOCORRECTION IN TREATMENT OF CHRONIC WOUNDS

In this article, we present results of local treatment of purulent wounds caused by various agents, in 232 patients, using local immunocorrection techniques combined with therapeutic application of nitrogen monoxide (NO). A series of immunological, cytological, microbiological researches have been c...

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Autores principales: M. A. Khalilov, I. A. Snimchsikova
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2014
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Acceso en línea:https://doaj.org/article/6468c86956fe46078b5ff41c95ebdf0f
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Sumario:In this article, we present results of local treatment of purulent wounds caused by various agents, in 232 patients, using local immunocorrection techniques combined with therapeutic application of nitrogen monoxide (NO). A series of immunological, cytological, microbiological researches have been carried out, showing a direct antibacterial effect of myelopid has been defined, and appropriate criteria have been developed for scoring intensity of inflammation affecting soft tissues. A justification for combined therapy with NО and myelopid has been obtained, and a method of local treatment of wound infections has been offered and patented. Basing on these experimental and clinical studies, as well as dynamic indices of wound process, we have shown a benefit from local immunocorrection by means of combined NО/myelopid treatment for complex therapy of purulent wounds.