Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes.
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Nature Portfolio
2021
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oai:doaj.org-article:6469cecdafd94ea58b6bbbc6fab63a442021-12-02T14:55:15ZInferring multilayer interactome networks shaping phenotypic plasticity and evolution10.1038/s41467-021-25086-52041-1723https://doaj.org/article/6469cecdafd94ea58b6bbbc6fab63a442021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25086-5https://doaj.org/toc/2041-1723Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes.Dengcheng YangYi JinXiaoqing HeAng DongJing WangRongling WuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
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Science Q Dengcheng Yang Yi Jin Xiaoqing He Ang Dong Jing Wang Rongling Wu Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
description |
Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes. |
format |
article |
author |
Dengcheng Yang Yi Jin Xiaoqing He Ang Dong Jing Wang Rongling Wu |
author_facet |
Dengcheng Yang Yi Jin Xiaoqing He Ang Dong Jing Wang Rongling Wu |
author_sort |
Dengcheng Yang |
title |
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
title_short |
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
title_full |
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
title_fullStr |
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
title_full_unstemmed |
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
title_sort |
inferring multilayer interactome networks shaping phenotypic plasticity and evolution |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/6469cecdafd94ea58b6bbbc6fab63a44 |
work_keys_str_mv |
AT dengchengyang inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution AT yijin inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution AT xiaoqinghe inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution AT angdong inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution AT jingwang inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution AT ronglingwu inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution |
_version_ |
1718389327657959424 |