Inferring multilayer interactome networks shaping phenotypic plasticity and evolution

Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes.

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Autores principales: Dengcheng Yang, Yi Jin, Xiaoqing He, Ang Dong, Jing Wang, Rongling Wu
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/6469cecdafd94ea58b6bbbc6fab63a44
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spelling oai:doaj.org-article:6469cecdafd94ea58b6bbbc6fab63a442021-12-02T14:55:15ZInferring multilayer interactome networks shaping phenotypic plasticity and evolution10.1038/s41467-021-25086-52041-1723https://doaj.org/article/6469cecdafd94ea58b6bbbc6fab63a442021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25086-5https://doaj.org/toc/2041-1723Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes.Dengcheng YangYi JinXiaoqing HeAng DongJing WangRongling WuNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Dengcheng Yang
Yi Jin
Xiaoqing He
Ang Dong
Jing Wang
Rongling Wu
Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
description Genetic plasticity drives phenotypic differences. Here, the authors develop a framework to quantify the individual and combinatorial contributions of SNPs on a phenotype of interest and use it to identify SNP-SNP interactions associated with variations in bacteria’s response to external changes.
format article
author Dengcheng Yang
Yi Jin
Xiaoqing He
Ang Dong
Jing Wang
Rongling Wu
author_facet Dengcheng Yang
Yi Jin
Xiaoqing He
Ang Dong
Jing Wang
Rongling Wu
author_sort Dengcheng Yang
title Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
title_short Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
title_full Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
title_fullStr Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
title_full_unstemmed Inferring multilayer interactome networks shaping phenotypic plasticity and evolution
title_sort inferring multilayer interactome networks shaping phenotypic plasticity and evolution
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/6469cecdafd94ea58b6bbbc6fab63a44
work_keys_str_mv AT dengchengyang inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
AT yijin inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
AT xiaoqinghe inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
AT angdong inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
AT jingwang inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
AT ronglingwu inferringmultilayerinteractomenetworksshapingphenotypicplasticityandevolution
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