Characterization of H5N1 Influenza Virus Variants with Hemagglutinin Mutations Isolated from Patients

Characterization of H5N1 Influenza Virus Variants with Hemagglutinin Mutations Isolated from Patients

ABSTRACT A change in viral hemagglutinin (HA) receptor binding specificity from α2,3- to α2,6-linked sialic acid is necessary for highly pathogenic avian influenza (AI) virus subtype H5N1 to become pandemic. However, details of the human-adaptive change in the H5N1 virus remain unknown. Our database...

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Autores principales: Yohei Watanabe, Yasuha Arai, Tomo Daidoji, Norihito Kawashita, Madiha S. Ibrahim, Emad El-Din M. El-Gendy, Hiroaki Hiramatsu, Ritsuko Kubota-Koketsu, Tatsuya Takagi, Takeomi Murata, Kazuo Takahashi, Yoshinobu Okuno, Takaaki Nakaya, Yasuo Suzuki, Kazuyoshi Ikuta
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2015
Materias:
Microbiology
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Acceso en línea:https://doaj.org/article/64717397769a42a5b96f86cc8cd161be
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