Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances

Abstract Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the proje...

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Autores principales:	Ilona Pavlovska, Aneka Klavina, Agris Auce, Ivars Vanadzins, Alise Silova, Laura Komarovska, Baiba Silamikele, Linda Dobkevica, Linda Paegle
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/6476ee600efe499f8da61b17733dc74c
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spelling	oai:doaj.org-article:6476ee600efe499f8da61b17733dc74c2021-12-02T15:11:51ZAssessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances10.1038/s41598-020-78498-62045-2322https://doaj.org/article/6476ee600efe499f8da61b17733dc74c2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41598-020-78498-6https://doaj.org/toc/2045-2322Abstract Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.Ilona PavlovskaAneka KlavinaAgris AuceIvars VanadzinsAlise SilovaLaura KomarovskaBaiba SilamikeleLinda DobkevicaLinda PaegleNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ilona Pavlovska Aneka Klavina Agris Auce Ivars Vanadzins Alise Silova Laura Komarovska Baiba Silamikele Linda Dobkevica Linda Paegle Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
description	Abstract Development trends need the necessity for wider use of the local resources and available natural materials are one of the priorities around the world. Freshwater sapropel is a common material in the water basement of the lakes, but still not sufficiently explored. The main goal of the project to start detailed and systematic research on the medical properties of sapropel to be obtained in Latvia, promote its scientifically based use in balneology, develop new medical procedures and services, and promote development of new exportable products. The results include the survey, sampling depths, and processing, evaluation of external signs, physical, chemical, and biochemical parameters, and evaluation of microbiological indicators. Active components from the sapropel samples extracted using the alkaline method. Sapropel extracts were characterized by organic carbon content, humic and fulvic acid concentrations, total phenolic content, trace metal and pesticide concentrations, total antioxidant status, and microbiological flora. Summarizing the article's main findings it was concluded that Latvian freshwater sapropel can be used as raw material for obtaining sapropel extract and use it in the preparation of pharmaceuticals and promote the development of new exportable products and services.
format	article
author	Ilona Pavlovska Aneka Klavina Agris Auce Ivars Vanadzins Alise Silova Laura Komarovska Baiba Silamikele Linda Dobkevica Linda Paegle
author_facet	Ilona Pavlovska Aneka Klavina Agris Auce Ivars Vanadzins Alise Silova Laura Komarovska Baiba Silamikele Linda Dobkevica Linda Paegle
author_sort	Ilona Pavlovska
title	Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_short	Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_full	Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_fullStr	Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_full_unstemmed	Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
title_sort	assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/6476ee600efe499f8da61b17733dc74c
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Assessment of sapropel use for pharmaceutical products according to legislation, pollution parameters, and concentration of biologically active substances

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