Rethinking the causes of pilonidal sinus disease: a matched cohort study

Abstract Our understanding of pilonidal sinus disease (PSD) is based on a paper published 29 years ago by Karydakis. Since then, surgeons have been taught that hair more easily penetrates wet skin, leading to the assumption that sweating promotes PSD. This postulate, however, has never been proven....

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Dietrich Doll, Imke Brengelmann, Patrick Schober, Andreas Ommer, Friederike Bosche, Apostolos E. Papalois, Sven Petersen, Dirk Wilhelm, Johannes Jongen, Markus M. Luedi
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/64776878d0b9488bb0d6765b3cd70845
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:64776878d0b9488bb0d6765b3cd70845
record_format	dspace
spelling	oai:doaj.org-article:64776878d0b9488bb0d6765b3cd708452021-12-02T11:39:39ZRethinking the causes of pilonidal sinus disease: a matched cohort study10.1038/s41598-021-85830-12045-2322https://doaj.org/article/64776878d0b9488bb0d6765b3cd708452021-03-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-85830-1https://doaj.org/toc/2045-2322Abstract Our understanding of pilonidal sinus disease (PSD) is based on a paper published 29 years ago by Karydakis. Since then, surgeons have been taught that hair more easily penetrates wet skin, leading to the assumption that sweating promotes PSD. This postulate, however, has never been proven. Thus we used pilocarpine iontophoresis to assess sweating in the glabella sacralis. 100 patients treated for PSD and 100 controls were matched for sex, age and body mass index (BMI). Pilocarpine iontophoresis was performed for 5 min, followed by 15 min of sweat collection. PSD patients sweated less than their matched pairs (18.4 ± 1.6 µl vs. 24.2 ± 2.1 µl, p = 0.03). Men sweated more than women (22.2 ± 1.2 µl vs. 15.0 ± 1.0 µl in non-PSD patients (p < 0.0001) and 20.0 ± 1.9 µl vs. 11.9 ± 2.0 µl in PSD patients (p = 0.051)). And regular exercisers sweated more than non-exercisers (29.1 ± 2.9 µl vs. 18.5 ± 1.6 µl, p = 0.0006 for men and 20.7 ± 2.3 µl vs. 11.4 ± 1.4 µl, p = 0.0005 for women). PSD patients sweat less than matched controls. Thus sweating may have a protective effect in PSD rather than being a risk factor.Dietrich DollImke BrengelmannPatrick SchoberAndreas OmmerFriederike BoscheApostolos E. PapaloisSven PetersenDirk WilhelmJohannes JongenMarkus M. LuediNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Dietrich Doll Imke Brengelmann Patrick Schober Andreas Ommer Friederike Bosche Apostolos E. Papalois Sven Petersen Dirk Wilhelm Johannes Jongen Markus M. Luedi Rethinking the causes of pilonidal sinus disease: a matched cohort study
description	Abstract Our understanding of pilonidal sinus disease (PSD) is based on a paper published 29 years ago by Karydakis. Since then, surgeons have been taught that hair more easily penetrates wet skin, leading to the assumption that sweating promotes PSD. This postulate, however, has never been proven. Thus we used pilocarpine iontophoresis to assess sweating in the glabella sacralis. 100 patients treated for PSD and 100 controls were matched for sex, age and body mass index (BMI). Pilocarpine iontophoresis was performed for 5 min, followed by 15 min of sweat collection. PSD patients sweated less than their matched pairs (18.4 ± 1.6 µl vs. 24.2 ± 2.1 µl, p = 0.03). Men sweated more than women (22.2 ± 1.2 µl vs. 15.0 ± 1.0 µl in non-PSD patients (p < 0.0001) and 20.0 ± 1.9 µl vs. 11.9 ± 2.0 µl in PSD patients (p = 0.051)). And regular exercisers sweated more than non-exercisers (29.1 ± 2.9 µl vs. 18.5 ± 1.6 µl, p = 0.0006 for men and 20.7 ± 2.3 µl vs. 11.4 ± 1.4 µl, p = 0.0005 for women). PSD patients sweat less than matched controls. Thus sweating may have a protective effect in PSD rather than being a risk factor.
format	article
author	Dietrich Doll Imke Brengelmann Patrick Schober Andreas Ommer Friederike Bosche Apostolos E. Papalois Sven Petersen Dirk Wilhelm Johannes Jongen Markus M. Luedi
author_facet	Dietrich Doll Imke Brengelmann Patrick Schober Andreas Ommer Friederike Bosche Apostolos E. Papalois Sven Petersen Dirk Wilhelm Johannes Jongen Markus M. Luedi
author_sort	Dietrich Doll
title	Rethinking the causes of pilonidal sinus disease: a matched cohort study
title_short	Rethinking the causes of pilonidal sinus disease: a matched cohort study
title_full	Rethinking the causes of pilonidal sinus disease: a matched cohort study
title_fullStr	Rethinking the causes of pilonidal sinus disease: a matched cohort study
title_full_unstemmed	Rethinking the causes of pilonidal sinus disease: a matched cohort study
title_sort	rethinking the causes of pilonidal sinus disease: a matched cohort study
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/64776878d0b9488bb0d6765b3cd70845
work_keys_str_mv	AT dietrichdoll rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT imkebrengelmann rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT patrickschober rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT andreasommer rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT friederikebosche rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT apostolosepapalois rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT svenpetersen rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT dirkwilhelm rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT johannesjongen rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy AT markusmluedi rethinkingthecausesofpilonidalsinusdiseaseamatchedcohortstudy
_version_	1718395703470850048

Rethinking the causes of pilonidal sinus disease: a matched cohort study

Ejemplares similares