Efficient Expression of HIV in Immunocompetent Mouse Brain Reveals a Novel Nonneurotoxic Viral Function in Hippocampal Synaptodendritic Injury and Memory Impairment
ABSTRACT HIV causes neurodegeneration and dementia in AIDS patients, but its function in milder cognitive impairments in virologically suppressed patients on antiretroviral therapy is unknown. Such patients are immunocompetent, have low peripheral and brain HIV burdens, and show minimal brain neurop...
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Autores principales: | Jennifer Kelschenbach, Hongxia He, Boe-Hyun Kim, Alejandra Borjabad, Chao-Jiang Gu, Wei Chao, Meilan Do, Leroy R. Sharer, Hong Zhang, Ottavio Arancio, Mary Jane Potash, David J. Volsky |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
American Society for Microbiology
2019
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Materias: | |
Acceso en línea: | https://doaj.org/article/647ff4c2424c40439623f7e83ef035e1 |
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