Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle

Said S, Putra WPB. 2018. Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle. Biodiversitas 19: 1622-1625. Heat stress in the livestock reduces repro...

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Autores principales:	SYAHRUDDIN SAID, WIDYA PINTAKA BAYU PUTRA
Formato:	article
Lenguaje:	EN
Publicado:	MBI & UNS Solo 2018
Materias:	bhsp70 gene pasundan cattle snp pic s/c Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/6480b6c317f74a7b87b19c06e88c3e91
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spelling	oai:doaj.org-article:6480b6c317f74a7b87b19c06e88c3e912021-11-16T14:04:05ZShort Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle1412-033X2085-472210.13057/biodiv/d190504https://doaj.org/article/6480b6c317f74a7b87b19c06e88c3e912018-09-01T00:00:00Zhttps://smujo.id/biodiv/article/view/2920https://doaj.org/toc/1412-033Xhttps://doaj.org/toc/2085-4722Said S, Putra WPB. 2018. Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle. Biodiversitas 19: 1622-1625. Heat stress in the livestock reduces reproductive traits, including of service per conception (S/C). The influence of heat stress in livestock can be handled through molecular selection. One of the candidate genes that is affecting heat stress tolerance is Bovine Heat Shock Protein 70 (bHSP70) gene. This research was carried out to detect the single nucleotide polymorphism (SNPs) in the 5'UTR of bHSP70 gene from 44 heads of Pasundan cows at breeding station (BPPIBT-SP Ciamis, West Java). Research showed that 18 SNPs were detected with sequencing method. The insertion mutation was detected in all animal studied and occurred at position between g.1112 and g.1113. The moderate of polymorphic informative content (PIC) were detected in two SNPs of g.1117G/A and g.1125A/C. Preliminary analysis showed that haplotype of two homozygote genotype combination from both SNPs had better of S/C value of than the others (P<0.01). Moreover, the average of S/C value in heterozygote genotype seems higher than homozygote genotype. However, the further research for clarification of this research results through large number of observation is important. It was concluded that two SNPs of g.1117G/A and g.1125A/C are potential as marker-assisted selection (MAS) for reproductive traits in Pasundan cows because of moderate PIC value.SYAHRUDDIN SAIDWIDYA PINTAKA BAYU PUTRAMBI & UNS Soloarticlebhsp70 genepasundan cattlesnppics/cBiology (General)QH301-705.5ENBiodiversitas, Vol 19, Iss 5, Pp 1622-1625 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	bhsp70 gene pasundan cattle snp pic s/c Biology (General) QH301-705.5
spellingShingle	bhsp70 gene pasundan cattle snp pic s/c Biology (General) QH301-705.5 SYAHRUDDIN SAID WIDYA PINTAKA BAYU PUTRA Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
description	Said S, Putra WPB. 2018. Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle. Biodiversitas 19: 1622-1625. Heat stress in the livestock reduces reproductive traits, including of service per conception (S/C). The influence of heat stress in livestock can be handled through molecular selection. One of the candidate genes that is affecting heat stress tolerance is Bovine Heat Shock Protein 70 (bHSP70) gene. This research was carried out to detect the single nucleotide polymorphism (SNPs) in the 5'UTR of bHSP70 gene from 44 heads of Pasundan cows at breeding station (BPPIBT-SP Ciamis, West Java). Research showed that 18 SNPs were detected with sequencing method. The insertion mutation was detected in all animal studied and occurred at position between g.1112 and g.1113. The moderate of polymorphic informative content (PIC) were detected in two SNPs of g.1117G/A and g.1125A/C. Preliminary analysis showed that haplotype of two homozygote genotype combination from both SNPs had better of S/C value of than the others (P<0.01). Moreover, the average of S/C value in heterozygote genotype seems higher than homozygote genotype. However, the further research for clarification of this research results through large number of observation is important. It was concluded that two SNPs of g.1117G/A and g.1125A/C are potential as marker-assisted selection (MAS) for reproductive traits in Pasundan cows because of moderate PIC value.
format	article
author	SYAHRUDDIN SAID WIDYA PINTAKA BAYU PUTRA
author_facet	SYAHRUDDIN SAID WIDYA PINTAKA BAYU PUTRA
author_sort	SYAHRUDDIN SAID
title	Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
title_short	Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
title_full	Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
title_fullStr	Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
title_full_unstemmed	Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle
title_sort	short communication: novel single nucleotide polymorphisms (snps) in the 5'utr of bovine heat shock protein 70 (bhsp70) gene and its association with service per conception (s/c) of pasundan cattle
publisher	MBI & UNS Solo
publishDate	2018
url	https://doaj.org/article/6480b6c317f74a7b87b19c06e88c3e91
work_keys_str_mv	AT syahruddinsaid shortcommunicationnovelsinglenucleotidepolymorphismssnpsinthe5utrofbovineheatshockprotein70bhsp70geneanditsassociationwithserviceperconceptionscofpasundancattle AT widyapintakabayuputra shortcommunicationnovelsinglenucleotidepolymorphismssnpsinthe5utrofbovineheatshockprotein70bhsp70geneanditsassociationwithserviceperconceptionscofpasundancattle
_version_	1718426426529546240

Short Communication: Novel Single Nucleotide Polymorphisms (SNPs) in the 5'UTR of Bovine Heat Shock Protein 70 (bHSP70) Gene and its association with Service per Conception (S/C) of Pasundan cattle

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