Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells

Reactive oxygen species (ROS) are required to initiate regeneration but the mechanisms regulating its production are unclear. Here, the authors show in zebrafish larval tail regeneration that ROS is released by mobilised notochord cells enables their repositioning in the damage site, assisted by sec...

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Autores principales:	Maria Montserrat Garcia Romero, Gareth McCathie, Philip Jankun, Henry Hamilton Roehl
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/6482a22186ff4ee6a121fb95a1c5d344
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spelling	oai:doaj.org-article:6482a22186ff4ee6a121fb95a1c5d3442021-12-02T17:31:29ZDamage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells10.1038/s41467-018-06460-22041-1723https://doaj.org/article/6482a22186ff4ee6a121fb95a1c5d3442018-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06460-2https://doaj.org/toc/2041-1723Reactive oxygen species (ROS) are required to initiate regeneration but the mechanisms regulating its production are unclear. Here, the authors show in zebrafish larval tail regeneration that ROS is released by mobilised notochord cells enables their repositioning in the damage site, assisted by secreted Hh.Maria Montserrat Garcia RomeroGareth McCathiePhilip JankunHenry Hamilton RoehlNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Montserrat Garcia Romero Gareth McCathie Philip Jankun Henry Hamilton Roehl Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
description	Reactive oxygen species (ROS) are required to initiate regeneration but the mechanisms regulating its production are unclear. Here, the authors show in zebrafish larval tail regeneration that ROS is released by mobilised notochord cells enables their repositioning in the damage site, assisted by secreted Hh.
format	article
author	Maria Montserrat Garcia Romero Gareth McCathie Philip Jankun Henry Hamilton Roehl
author_facet	Maria Montserrat Garcia Romero Gareth McCathie Philip Jankun Henry Hamilton Roehl
author_sort	Maria Montserrat Garcia Romero
title	Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
title_short	Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
title_full	Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
title_fullStr	Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
title_full_unstemmed	Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells
title_sort	damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of hedgehog expressing cells
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/6482a22186ff4ee6a121fb95a1c5d344
work_keys_str_mv	AT mariamontserratgarciaromero damageinducedreactiveoxygenspeciesenablezebrafishtailregenerationbyrepositioningofhedgehogexpressingcells AT garethmccathie damageinducedreactiveoxygenspeciesenablezebrafishtailregenerationbyrepositioningofhedgehogexpressingcells AT philipjankun damageinducedreactiveoxygenspeciesenablezebrafishtailregenerationbyrepositioningofhedgehogexpressingcells AT henryhamiltonroehl damageinducedreactiveoxygenspeciesenablezebrafishtailregenerationbyrepositioningofhedgehogexpressingcells
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Damage-induced reactive oxygen species enable zebrafish tail regeneration by repositioning of Hedgehog expressing cells

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