Rapamycin attenuates PLA2R activation-mediated podocyte apoptosis via the PI3K/AKT/mTOR pathway

Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults without diabetes. Primary MN has been associated with circulating antibodies against native podocyte antigens, including phospholipase A2 receptor (PLA2R); however, precision therapy targeting the signaling cascade...

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Autores principales: Terry Ting-Yu Chiou, You-Ying Chau, Jin-Bor Chen, Hsiang-Hao Hsu, Shao-Pei Hung, Wen-Chin Lee
Formato: article
Lenguaje:EN
Publicado: Elsevier 2021
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Acceso en línea:https://doaj.org/article/6483ea9e50d64b349c7b6ac6dac6e2ab
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