A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.

Clostridium difficile is the etiological agent of antibiotic-associated diarrhoea (AAD) and pseudomembranous colitis in humans. The role of the surface layer proteins (SLPs) in this disease has not yet been fully explored. The aim of this study was to investigate a role for SLPs in the recognition o...

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Bibliographic Details
Main Authors:	Anthony Ryan, Mark Lynch, Sinead M Smith, Sylvie Amu, Hendrik J Nel, Claire E McCoy, Jennifer K Dowling, Eve Draper, Vincent O'Reilly, Ciara McCarthy, Julie O'Brien, Déirdre Ní Eidhin, Mary J O'Connell, Brian Keogh, Charles O Morton, Thomas R Rogers, Padraic G Fallon, Luke A O'Neill, Dermot Kelleher, Christine E Loscher
Format:	article
Language:	EN
Published:	Public Library of Science (PLoS) 2011
Subjects:	Immunologic diseases. Allergy RC581-607 Biology (General) QH301-705.5
Online Access:	https://doaj.org/article/6486bcb3a30d4095ab5596eb0047788c
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A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.

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