Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma

Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma

Eleni Bagli, Christos Gartzios, Ioannis Asproudis, Georgios KitsosUniversity Eye Clinic of Ioannina, Ioannina, GreecePurpose: The comparison of one-site versus two-site phacotrabeculectomy in patients with pseudoexfoliation glaucoma (PEXG) and primary open-angle glaucoma (POAG), with respect to intr...

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Autores principales: Eleni Bagli, Christos Gartzios, Ioannis Asproudis, Georgios Kitsos
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2009
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Ophthalmology
RE1-994
Acceso en línea:https://doaj.org/article/6494c18b75374c28b19b2c2b36808825
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spelling oai:doaj.org-article:6494c18b75374c28b19b2c2b368088252021-12-02T01:34:33ZComparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma1177-54671177-5483https://doaj.org/article/6494c18b75374c28b19b2c2b368088252009-04-01T00:00:00Zhttp://www.dovepress.com/comparison-of-one-site-versus-two-site-phacotrabeculectomy-without-the-a3014https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Eleni Bagli, Christos Gartzios, Ioannis Asproudis, Georgios KitsosUniversity Eye Clinic of Ioannina, Ioannina, GreecePurpose: The comparison of one-site versus two-site phacotrabeculectomy in patients with pseudoexfoliation glaucoma (PEXG) and primary open-angle glaucoma (POAG), with respect to intraocular pressure (IOP), antiglaucomatous medication (AM) requirements and visual acuity (VA).Methods: Forty-seven patients (eyes) with cataract and POAG and 46 sex- and age-matched patients with cataract and PEXG were randomized to one- or two-site phacotrabeculectomy and reviewed with a follow-up at three years.Results: Mean preoperative IOP was 22.04 ± 2.27 mmHg and 22.92 ± 2.35 mmHg in POAG and PEXG groups (p > 0.05) using a mean of 2.76 ± 0.74, 2.74 ± 0.69 AM, respectively (p > 0.05). After three years of follow-up, the mean IOP was 15.04 ± 1.57 mmHg in the one-site, 15.04 ± 1.99 mmHg in the two-site group with POAG, 15 ± 1.8 mmHg in the one-site, 15.32 ± 1.31 mmHg in the two-site group with PEXG, using a mean of 0.68 ± 0.69, 0.84 ± 0.75, 0.96 ± 0.67, and 0.8 ± 0.62 AM, respectively. Mean IOP and AM postoperatively were significantly less compared to preoperatively for each group (p < 0.05). No difference was observed in mean IOP and AM between the four groups at three years postoperatively (p > 0.05). VA improved similarly in four groups at the three-year follow-up (p < 0.05). Intraoperative, postoperative complications, and need for 5-fluorouracil injections were similar between the surgical groups.Conclusion: One-site and two-site phacotrabeculectomy without the use of antimetabolites intraoperatively were similarly safe and effective in IOP control over a three-year follow-up period in patients with POAG and PEXG.Keywords: phacotrabeculectomy, pseudoexfoliation, glaucoma Eleni BagliChristos GartziosIoannis AsproudisGeorgios KitsosDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2009, Iss default, Pp 297-305 (2009)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Eleni Bagli
Christos Gartzios
Ioannis Asproudis
Georgios Kitsos
Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
description Eleni Bagli, Christos Gartzios, Ioannis Asproudis, Georgios KitsosUniversity Eye Clinic of Ioannina, Ioannina, GreecePurpose: The comparison of one-site versus two-site phacotrabeculectomy in patients with pseudoexfoliation glaucoma (PEXG) and primary open-angle glaucoma (POAG), with respect to intraocular pressure (IOP), antiglaucomatous medication (AM) requirements and visual acuity (VA).Methods: Forty-seven patients (eyes) with cataract and POAG and 46 sex- and age-matched patients with cataract and PEXG were randomized to one- or two-site phacotrabeculectomy and reviewed with a follow-up at three years.Results: Mean preoperative IOP was 22.04 ± 2.27 mmHg and 22.92 ± 2.35 mmHg in POAG and PEXG groups (p > 0.05) using a mean of 2.76 ± 0.74, 2.74 ± 0.69 AM, respectively (p > 0.05). After three years of follow-up, the mean IOP was 15.04 ± 1.57 mmHg in the one-site, 15.04 ± 1.99 mmHg in the two-site group with POAG, 15 ± 1.8 mmHg in the one-site, 15.32 ± 1.31 mmHg in the two-site group with PEXG, using a mean of 0.68 ± 0.69, 0.84 ± 0.75, 0.96 ± 0.67, and 0.8 ± 0.62 AM, respectively. Mean IOP and AM postoperatively were significantly less compared to preoperatively for each group (p < 0.05). No difference was observed in mean IOP and AM between the four groups at three years postoperatively (p > 0.05). VA improved similarly in four groups at the three-year follow-up (p < 0.05). Intraoperative, postoperative complications, and need for 5-fluorouracil injections were similar between the surgical groups.Conclusion: One-site and two-site phacotrabeculectomy without the use of antimetabolites intraoperatively were similarly safe and effective in IOP control over a three-year follow-up period in patients with POAG and PEXG.Keywords: phacotrabeculectomy, pseudoexfoliation, glaucoma
format article
author Eleni Bagli
Christos Gartzios
Ioannis Asproudis
Georgios Kitsos
author_facet Eleni Bagli
Christos Gartzios
Ioannis Asproudis
Georgios Kitsos
author_sort Eleni Bagli
title Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
title_short Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
title_full Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
title_fullStr Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
title_full_unstemmed Comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
title_sort comparison of one-site versus two-site phacotrabeculectomy without the use of antimetabolites intraoperatively in patients with pseudoexfoliation glaucoma and primary open-angle glaucoma
publisher Dove Medical Press
publishDate 2009
url https://doaj.org/article/6494c18b75374c28b19b2c2b36808825
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AT christosgartzios comparisonofonesiteversustwositephacotrabeculectomywithouttheuseofantimetabolitesintraoperativelyinpatientswithpseudoexfoliationglaucomaandprimaryopenangleglaucoma
AT ioannisasproudis comparisonofonesiteversustwositephacotrabeculectomywithouttheuseofantimetabolitesintraoperativelyinpatientswithpseudoexfoliationglaucomaandprimaryopenangleglaucoma
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