Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes

Haya M Al-Farhan, Wafa’a Majed Al-OtaibiDepartment of Optometry and Vision Sciences, College of Applied Medicine Science, King Saud University, Riyadh, Kingdom of Saudia ArabiaPurpose: To compare the precision of central corneal thickness (CCT) measurements taken with the handheld ultr...

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Autores principales: Al-Farhan HM, Al-Otaibi WM
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spelling oai:doaj.org-article:6495440041a444818acd3a03e05b61ab2021-12-02T02:30:54ZComparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes1177-54671177-5483https://doaj.org/article/6495440041a444818acd3a03e05b61ab2012-07-01T00:00:00Zhttp://www.dovepress.com/comparison-of-central-corneal-thickness-measurements-using-ultrasound--a10327https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Haya M Al-Farhan, Wafa’a Majed Al-OtaibiDepartment of Optometry and Vision Sciences, College of Applied Medicine Science, King Saud University, Riyadh, Kingdom of Saudia ArabiaPurpose: To compare the precision of central corneal thickness (CCT) measurements taken with the handheld ultrasound pachymeter (USP), ultrasound biomicroscopy (UBM), and the Artemis-2 very high frequency ultrasound scanner (VHFUS) on normal subjects.Design: Prospective study.Methods: One eye from each of 61 normal subjects was randomly selected for this study. The measurements of the CCT were taken with the USP, VHFUS, and UBM. Results were compared statistically using repeated-measures analysis of variance (ANOVA), Pearson’s correlation coefficient, and limits of agreement.Results: The average CCT (± standard deviation) was 530.1 ± 30.5 µm, 554.9 ± 31.7 µm, and 559.5 ± 30.7 µm for UBM, VHFUS, and USP respectively. The intraobserver repeatability analyses of variance are not significant for USP, UBM, and VHFUS. P-values were 0.17, 0.19, and 0.37 respectively. Repeated-measures ANOVA showed a significant difference between the three different methods of measuring CCT (P = 0.0001). The ANOVA test revealed no statistically significant difference between USP and VHFUS (P > 0.05), yet statistical significant differences with UBM versus USP and UBM versus VHFUS (P < 0.001). There were high correlations between the three instruments (P < 0.0001). The mean differences (and upper/lower limits of agreement) for CCT measurements were 29.4 ± 14.3 (2.7/56), 4.6 ± 8.6 (-14.7/23.8), and -24.8 ± 13.1 (-50.4/0.8) for USP versus UBM, USP versus VHFUS, and UBM versus VHFUS, respectively.Conclusion: The UBM produces CCT measurements that vary significantly from those returned by the USP and the VHFUS, suggesting that the UBM may not be used interchangeably with either equipment for monitoring the CCT in the clinical setting.Keywords: central corneal thickness, ultrasound pachymetry, ultrasound biomicroscopy, Artemis-2 VHFUS, Artemis, normal eyesAl-Farhan HMAl-Otaibi WMDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2012, Iss default, Pp 1037-1043 (2012)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Al-Farhan HM
Al-Otaibi WM
Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
description Haya M Al-Farhan, Wafa’a Majed Al-OtaibiDepartment of Optometry and Vision Sciences, College of Applied Medicine Science, King Saud University, Riyadh, Kingdom of Saudia ArabiaPurpose: To compare the precision of central corneal thickness (CCT) measurements taken with the handheld ultrasound pachymeter (USP), ultrasound biomicroscopy (UBM), and the Artemis-2 very high frequency ultrasound scanner (VHFUS) on normal subjects.Design: Prospective study.Methods: One eye from each of 61 normal subjects was randomly selected for this study. The measurements of the CCT were taken with the USP, VHFUS, and UBM. Results were compared statistically using repeated-measures analysis of variance (ANOVA), Pearson’s correlation coefficient, and limits of agreement.Results: The average CCT (± standard deviation) was 530.1 ± 30.5 µm, 554.9 ± 31.7 µm, and 559.5 ± 30.7 µm for UBM, VHFUS, and USP respectively. The intraobserver repeatability analyses of variance are not significant for USP, UBM, and VHFUS. P-values were 0.17, 0.19, and 0.37 respectively. Repeated-measures ANOVA showed a significant difference between the three different methods of measuring CCT (P = 0.0001). The ANOVA test revealed no statistically significant difference between USP and VHFUS (P > 0.05), yet statistical significant differences with UBM versus USP and UBM versus VHFUS (P < 0.001). There were high correlations between the three instruments (P < 0.0001). The mean differences (and upper/lower limits of agreement) for CCT measurements were 29.4 ± 14.3 (2.7/56), 4.6 ± 8.6 (-14.7/23.8), and -24.8 ± 13.1 (-50.4/0.8) for USP versus UBM, USP versus VHFUS, and UBM versus VHFUS, respectively.Conclusion: The UBM produces CCT measurements that vary significantly from those returned by the USP and the VHFUS, suggesting that the UBM may not be used interchangeably with either equipment for monitoring the CCT in the clinical setting.Keywords: central corneal thickness, ultrasound pachymetry, ultrasound biomicroscopy, Artemis-2 VHFUS, Artemis, normal eyes
format article
author Al-Farhan HM
Al-Otaibi WM
author_facet Al-Farhan HM
Al-Otaibi WM
author_sort Al-Farhan HM
title Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
title_short Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
title_full Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
title_fullStr Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
title_full_unstemmed Comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the Artemis-2 VHF scanner in normal eyes
title_sort comparison of central corneal thickness measurements using ultrasound pachymetry, ultrasound biomicroscopy, and the artemis-2 vhf scanner in normal eyes
publisher Dove Medical Press
publishDate 2012
url https://doaj.org/article/6495440041a444818acd3a03e05b61ab
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