β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity

During insulin-resistance, the compensatory expansion of beta-cell mass is able to delay or the onset of overt type 2 diabetes. Here, the authors report that beta-arrestin-1, an intracellular protein known to regulate signalling through G protein-coupled receptors, is essential for beta-cell replica...

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Autores principales: Luiz F. Barella, Mario Rossi, Sai P. Pydi, Jaroslawna Meister, Shanu Jain, Yinghong Cui, Oksana Gavrilova, Gianluca Fulgenzi, Lino Tessarollo, Jürgen Wess
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Science
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Acceso en línea:https://doaj.org/article/6495975e0d934f97876f1a64e6b60529
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