Uropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

Uropathogenic <named-content content-type="genus-species">Escherichia coli</named-content> Metabolite-Dependent Quiescence and Persistence May Explain Antibiotic Tolerance during Urinary Tract Infection

ABSTRACT In the present study, it is shown that although Escherichia coli CFT073, a human uropathogenic (UPEC) strain, grows in liquid glucose M9 minimal medium, it fails to grow on glucose M9 minimal medium agar plates seeded with ≤106 CFU. The cells on glucose plates appear to be in a “quiescent”...

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Autores principales: Mary P. Leatham-Jensen, Matthew E. Mokszycki, David C. Rowley, Robert Deering, Jodi L. Camberg, Evgeni V. Sokurenko, Veronika L. Tchesnokova, Jakob Frimodt-Møller, Karen A. Krogfelt, Karen Leth Nielsen, Niels Frimodt-Møller, Gongqin Sun, Paul S. Cohen
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
E. coli quiescence
E. coli persistence
urinary tract infections
carbon metabolism
TCA cycle
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/6497ab76beaa4d5e949dc9769acc0652
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