Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications

IgG that is produced by mammalian species can be replaced by obtained immunoglobulin Y from egg yolk. The egg yolk of immunized chickens is a rich and inexpensive source of specific polyclonal antibodies. Chickens respond to conserved mammalian antigens better, IgY doesn’t react with rheumatoid fact...

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Autor principal: M Pour Amir
Formato: article
Lenguaje:EN
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Publicado: Babol University of Medical Sciences 2001
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Acceso en línea:https://doaj.org/article/64982281056a45f9ade4e95a80f7e1c2
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spelling oai:doaj.org-article:64982281056a45f9ade4e95a80f7e1c22021-11-10T09:21:06ZImmunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications1561-41072251-7170https://doaj.org/article/64982281056a45f9ade4e95a80f7e1c22001-07-01T00:00:00Zhttp://jbums.org/article-1-2865-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170IgG that is produced by mammalian species can be replaced by obtained immunoglobulin Y from egg yolk. The egg yolk of immunized chickens is a rich and inexpensive source of specific polyclonal antibodies. Chickens respond to conserved mammalian antigens better, IgY doesn’t react with rheumatoid factors, bacteria and mammalian FC receptors. It reduces false-positive cases. But, the major problem in isolation is removal of lipids, which are in high concentrations. Several methods could be used for isolation and purification of IgY from egg yolk such as water dilution and T-gel chromatography. IgY can be useful in immunodiagnosis and therapy.M Pour AmirBabol University of Medical Sciencesarticleimmunoglobulin yisolationpurificationdiagnosistherapyMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 3, Iss 3, Pp 47-54 (2001)
institution DOAJ
collection DOAJ
language EN
FA
topic immunoglobulin y
isolation
purification
diagnosis
therapy
Medicine
R
Medicine (General)
R5-920
spellingShingle immunoglobulin y
isolation
purification
diagnosis
therapy
Medicine
R
Medicine (General)
R5-920
M Pour Amir
Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
description IgG that is produced by mammalian species can be replaced by obtained immunoglobulin Y from egg yolk. The egg yolk of immunized chickens is a rich and inexpensive source of specific polyclonal antibodies. Chickens respond to conserved mammalian antigens better, IgY doesn’t react with rheumatoid factors, bacteria and mammalian FC receptors. It reduces false-positive cases. But, the major problem in isolation is removal of lipids, which are in high concentrations. Several methods could be used for isolation and purification of IgY from egg yolk such as water dilution and T-gel chromatography. IgY can be useful in immunodiagnosis and therapy.
format article
author M Pour Amir
author_facet M Pour Amir
author_sort M Pour Amir
title Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
title_short Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
title_full Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
title_fullStr Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
title_full_unstemmed Immunoglobulin Y (IgY) from egg yolk: From molecular structures to medical applications
title_sort immunoglobulin y (igy) from egg yolk: from molecular structures to medical applications
publisher Babol University of Medical Sciences
publishDate 2001
url https://doaj.org/article/64982281056a45f9ade4e95a80f7e1c2
work_keys_str_mv AT mpouramir immunoglobulinyigyfromeggyolkfrommolecularstructurestomedicalapplications
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