Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation

Background: Myocardial infarction is a daily challenging emergency. Proper diagnosis and intervention in a timely manner is crucial. The aim of the work: We aimed to detect the impact of primary percutaneous coronary intervention [PPCI] on the development and severity of mitral valve regurgitatio...

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Autores principales:	Mohammad Aly Hammad, Mansour Mohammad Mustafa, Mohamed Adel Attia, Muhammad Saad Reihan, Ebrahim Farajallah Said
Formato:	article
Lenguaje:	EN
Publicado:	Al-Azhar University, Faculty of Medicine (Damietta) 2021
Materias:	primary pci stemi acute myocardial infarction ischemic mitral regurgitation Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/64a85021ccb04a3e99a8b3afa6f29e35
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spelling	oai:doaj.org-article:64a85021ccb04a3e99a8b3afa6f29e352021-12-02T17:16:01ZPrimary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation2636-41742682-378010.21608/ijma.2021.50324.1210https://doaj.org/article/64a85021ccb04a3e99a8b3afa6f29e352021-04-01T00:00:00Zhttps://ijma.journals.ekb.eg/article_160238_69373c2c73e6c8a191b11f22b73332be.pdfhttps://doaj.org/toc/2636-4174https://doaj.org/toc/2682-3780Background: Myocardial infarction is a daily challenging emergency. Proper diagnosis and intervention in a timely manner is crucial. The aim of the work: We aimed to detect the impact of primary percutaneous coronary intervention [PPCI] on the development and severity of mitral valve regurgitation in patients presenting with acute myocardial infarction with ST-segment elevation [STEMI]. Patients and Methods: This was a cross-sectional comparative study that was conducted from January 2018 to November 2019 at the Department of Cardiology, Al-Azhar University Hospital, Damietta, Egypt. Patients were divided into four groups; Group I: STEMI patients with PPCI and single-vessel disease; Group II: STEMI patients with PPCI of culprit vessel and staged PCI with in-hospital admission; Group III: STEMI patients with streptokinase and pharmaco-invasive PCI of the single vessel; Group IV: STEMI patients with streptokinase and multi-vessel PCI at the same session. Results: One-hundred and five patients were included in this study. Patients in group I showed a significant improvement after six months of follow-up in terms of ejection fraction [p <0.001]. Regarding the coaptation height, it showed a significant elevation in group I [p <0.001], and a significant reduction in group II [p <0.001] and III [p=0.013]. Similarly, PISA reduced significantly after six months in group I [p <0.001], II [p=0.002], and IV [p=0.007]. EPSS was reduced significantly in group I [p=0.0004]. Likewise, the distance of intrapapillary showed a significant reduction in group I [p <0.001]. Regarding the regurgitant area, it was significantly [p <0.05] reduced in all groups. Conclusion: Our results showed that PPCI could decrease the incidence and the severity of IMR and improve IMR parameters, especially in patients with acute STEMI. Further well-designed longitudinal studies with a larger sample size are required to evaluate these findings.Mohammad Aly HammadMansour Mohammad MustafaMohamed Adel AttiaMuhammad Saad ReihanEbrahim Farajallah SaidAl-Azhar University, Faculty of Medicine (Damietta)articleprimary pcistemiacute myocardial infarctionischemic mitral regurgitationMedicine (General)R5-920ENInternational Journal of Medical Arts, Vol 3, Iss 2, Pp 1437-1446 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	primary pci stemi acute myocardial infarction ischemic mitral regurgitation Medicine (General) R5-920
spellingShingle	primary pci stemi acute myocardial infarction ischemic mitral regurgitation Medicine (General) R5-920 Mohammad Aly Hammad Mansour Mohammad Mustafa Mohamed Adel Attia Muhammad Saad Reihan Ebrahim Farajallah Said Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
description	Background: Myocardial infarction is a daily challenging emergency. Proper diagnosis and intervention in a timely manner is crucial. The aim of the work: We aimed to detect the impact of primary percutaneous coronary intervention [PPCI] on the development and severity of mitral valve regurgitation in patients presenting with acute myocardial infarction with ST-segment elevation [STEMI]. Patients and Methods: This was a cross-sectional comparative study that was conducted from January 2018 to November 2019 at the Department of Cardiology, Al-Azhar University Hospital, Damietta, Egypt. Patients were divided into four groups; Group I: STEMI patients with PPCI and single-vessel disease; Group II: STEMI patients with PPCI of culprit vessel and staged PCI with in-hospital admission; Group III: STEMI patients with streptokinase and pharmaco-invasive PCI of the single vessel; Group IV: STEMI patients with streptokinase and multi-vessel PCI at the same session. Results: One-hundred and five patients were included in this study. Patients in group I showed a significant improvement after six months of follow-up in terms of ejection fraction [p <0.001]. Regarding the coaptation height, it showed a significant elevation in group I [p <0.001], and a significant reduction in group II [p <0.001] and III [p=0.013]. Similarly, PISA reduced significantly after six months in group I [p <0.001], II [p=0.002], and IV [p=0.007]. EPSS was reduced significantly in group I [p=0.0004]. Likewise, the distance of intrapapillary showed a significant reduction in group I [p <0.001]. Regarding the regurgitant area, it was significantly [p <0.05] reduced in all groups. Conclusion: Our results showed that PPCI could decrease the incidence and the severity of IMR and improve IMR parameters, especially in patients with acute STEMI. Further well-designed longitudinal studies with a larger sample size are required to evaluate these findings.
format	article
author	Mohammad Aly Hammad Mansour Mohammad Mustafa Mohamed Adel Attia Muhammad Saad Reihan Ebrahim Farajallah Said
author_facet	Mohammad Aly Hammad Mansour Mohammad Mustafa Mohamed Adel Attia Muhammad Saad Reihan Ebrahim Farajallah Said
author_sort	Mohammad Aly Hammad
title	Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
title_short	Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
title_full	Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
title_fullStr	Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
title_full_unstemmed	Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation
title_sort	primary percutaneous coronary intervention for acute myocardial infarction with st segment-elevation: effect on the severity of ischemic mitral regurgitation
publisher	Al-Azhar University, Faculty of Medicine (Damietta)
publishDate	2021
url	https://doaj.org/article/64a85021ccb04a3e99a8b3afa6f29e35
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Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction with ST Segment-Elevation: Effect on the Severity of Ischemic Mitral Regurgitation

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