Rifampin phosphotransferase is an unusual antibiotic resistance kinase

Antibiotic resistance is a major clinical problem that threatens to undermine our ability to control infectious diseases. Here the authors present detailed structural analysis of Rifampin phosphotransferase from Listeria monocytogenes, yielding insight on how this class of enzyme inactivates its tar...

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Autores principales:	Peter J. Stogios, Georgina Cox, Peter Spanogiannopoulos, Monica C. Pillon, Nicholas Waglechner, Tatiana Skarina, Kalinka Koteva, Alba Guarné, Alexei Savchenko, Gerard D. Wright
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/64b0a2b6d6ba4b86bd0e1b03eb366200
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spelling	oai:doaj.org-article:64b0a2b6d6ba4b86bd0e1b03eb3662002021-12-02T14:39:13ZRifampin phosphotransferase is an unusual antibiotic resistance kinase10.1038/ncomms113432041-1723https://doaj.org/article/64b0a2b6d6ba4b86bd0e1b03eb3662002016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11343https://doaj.org/toc/2041-1723Antibiotic resistance is a major clinical problem that threatens to undermine our ability to control infectious diseases. Here the authors present detailed structural analysis of Rifampin phosphotransferase from Listeria monocytogenes, yielding insight on how this class of enzyme inactivates its target antibiotics.Peter J. StogiosGeorgina CoxPeter SpanogiannopoulosMonica C. PillonNicholas WaglechnerTatiana SkarinaKalinka KotevaAlba GuarnéAlexei SavchenkoGerard D. WrightNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Peter J. Stogios Georgina Cox Peter Spanogiannopoulos Monica C. Pillon Nicholas Waglechner Tatiana Skarina Kalinka Koteva Alba Guarné Alexei Savchenko Gerard D. Wright Rifampin phosphotransferase is an unusual antibiotic resistance kinase
description	Antibiotic resistance is a major clinical problem that threatens to undermine our ability to control infectious diseases. Here the authors present detailed structural analysis of Rifampin phosphotransferase from Listeria monocytogenes, yielding insight on how this class of enzyme inactivates its target antibiotics.
format	article
author	Peter J. Stogios Georgina Cox Peter Spanogiannopoulos Monica C. Pillon Nicholas Waglechner Tatiana Skarina Kalinka Koteva Alba Guarné Alexei Savchenko Gerard D. Wright
author_facet	Peter J. Stogios Georgina Cox Peter Spanogiannopoulos Monica C. Pillon Nicholas Waglechner Tatiana Skarina Kalinka Koteva Alba Guarné Alexei Savchenko Gerard D. Wright
author_sort	Peter J. Stogios
title	Rifampin phosphotransferase is an unusual antibiotic resistance kinase
title_short	Rifampin phosphotransferase is an unusual antibiotic resistance kinase
title_full	Rifampin phosphotransferase is an unusual antibiotic resistance kinase
title_fullStr	Rifampin phosphotransferase is an unusual antibiotic resistance kinase
title_full_unstemmed	Rifampin phosphotransferase is an unusual antibiotic resistance kinase
title_sort	rifampin phosphotransferase is an unusual antibiotic resistance kinase
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/64b0a2b6d6ba4b86bd0e1b03eb366200
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Rifampin phosphotransferase is an unusual antibiotic resistance kinase

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