Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells
Non-viral vectors are important for transfection but can be limited in the uptake, protection and release of ssDNA. Here, the authors report on the design of metal-organic-framework vectors with precisely controlled pore geometry and demonstrate the vector in the transfection of immune cells.
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Nature Portfolio
2018
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oai:doaj.org-article:64ba95d8d87f433fb0c97c49bbd8a5f82021-12-02T14:39:28ZMetal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells10.1038/s41467-018-03650-w2041-1723https://doaj.org/article/64ba95d8d87f433fb0c97c49bbd8a5f82018-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03650-whttps://doaj.org/toc/2041-1723Non-viral vectors are important for transfection but can be limited in the uptake, protection and release of ssDNA. Here, the authors report on the design of metal-organic-framework vectors with precisely controlled pore geometry and demonstrate the vector in the transfection of immune cells.Shuang PengBinglin BieYangzesheng SunMin LiuHengjiang CongWentao ZhouYucong XiaHeng TangHexiang DengXiang ZhouNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018) |
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Science Q |
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Science Q Shuang Peng Binglin Bie Yangzesheng Sun Min Liu Hengjiang Cong Wentao Zhou Yucong Xia Heng Tang Hexiang Deng Xiang Zhou Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
description |
Non-viral vectors are important for transfection but can be limited in the uptake, protection and release of ssDNA. Here, the authors report on the design of metal-organic-framework vectors with precisely controlled pore geometry and demonstrate the vector in the transfection of immune cells. |
format |
article |
author |
Shuang Peng Binglin Bie Yangzesheng Sun Min Liu Hengjiang Cong Wentao Zhou Yucong Xia Heng Tang Hexiang Deng Xiang Zhou |
author_facet |
Shuang Peng Binglin Bie Yangzesheng Sun Min Liu Hengjiang Cong Wentao Zhou Yucong Xia Heng Tang Hexiang Deng Xiang Zhou |
author_sort |
Shuang Peng |
title |
Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
title_short |
Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
title_full |
Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
title_fullStr |
Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
title_full_unstemmed |
Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells |
title_sort |
metal-organic frameworks for precise inclusion of single-stranded dna and transfection in immune cells |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/64ba95d8d87f433fb0c97c49bbd8a5f8 |
work_keys_str_mv |
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