Metal-organic frameworks for precise inclusion of single-stranded DNA and transfection in immune cells

Non-viral vectors are important for transfection but can be limited in the uptake, protection and release of ssDNA. Here, the authors report on the design of metal-organic-framework vectors with precisely controlled pore geometry and demonstrate the vector in the transfection of immune cells.

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Autores principales: Shuang Peng, Binglin Bie, Yangzesheng Sun, Min Liu, Hengjiang Cong, Wentao Zhou, Yucong Xia, Heng Tang, Hexiang Deng, Xiang Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/64ba95d8d87f433fb0c97c49bbd8a5f8
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