Concepts of extracellular matrix remodelling in tumour progression and metastasis

Tumors are more than cancer cells — the extracellular matrix is a protein structure that organizes all tissues and is altered in cancer. Here, the authors review recent progress in understanding how the cancer cells and tumor-associated stroma cells remodel the extracellular matrix to drive tumor gr...

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Autores principales:	Juliane Winkler, Abisola Abisoye-Ogunniyan, Kevin J. Metcalf, Zena Werb
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/64c57786027e46eeaaca470666599a22
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spelling	oai:doaj.org-article:64c57786027e46eeaaca470666599a222021-12-02T18:37:17ZConcepts of extracellular matrix remodelling in tumour progression and metastasis10.1038/s41467-020-18794-x2041-1723https://doaj.org/article/64c57786027e46eeaaca470666599a222020-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18794-xhttps://doaj.org/toc/2041-1723Tumors are more than cancer cells — the extracellular matrix is a protein structure that organizes all tissues and is altered in cancer. Here, the authors review recent progress in understanding how the cancer cells and tumor-associated stroma cells remodel the extracellular matrix to drive tumor growth and metastasis.Juliane WinklerAbisola Abisoye-OgunniyanKevin J. MetcalfZena WerbNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Juliane Winkler Abisola Abisoye-Ogunniyan Kevin J. Metcalf Zena Werb Concepts of extracellular matrix remodelling in tumour progression and metastasis
description	Tumors are more than cancer cells — the extracellular matrix is a protein structure that organizes all tissues and is altered in cancer. Here, the authors review recent progress in understanding how the cancer cells and tumor-associated stroma cells remodel the extracellular matrix to drive tumor growth and metastasis.
format	article
author	Juliane Winkler Abisola Abisoye-Ogunniyan Kevin J. Metcalf Zena Werb
author_facet	Juliane Winkler Abisola Abisoye-Ogunniyan Kevin J. Metcalf Zena Werb
author_sort	Juliane Winkler
title	Concepts of extracellular matrix remodelling in tumour progression and metastasis
title_short	Concepts of extracellular matrix remodelling in tumour progression and metastasis
title_full	Concepts of extracellular matrix remodelling in tumour progression and metastasis
title_fullStr	Concepts of extracellular matrix remodelling in tumour progression and metastasis
title_full_unstemmed	Concepts of extracellular matrix remodelling in tumour progression and metastasis
title_sort	concepts of extracellular matrix remodelling in tumour progression and metastasis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/64c57786027e46eeaaca470666599a22
work_keys_str_mv	AT julianewinkler conceptsofextracellularmatrixremodellingintumourprogressionandmetastasis AT abisolaabisoyeogunniyan conceptsofextracellularmatrixremodellingintumourprogressionandmetastasis AT kevinjmetcalf conceptsofextracellularmatrixremodellingintumourprogressionandmetastasis AT zenawerb conceptsofextracellularmatrixremodellingintumourprogressionandmetastasis
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Concepts of extracellular matrix remodelling in tumour progression and metastasis

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