Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge

The most lethal adverse effect of COVID-19 is acute respiratory distress syndrome, which can lead to rapid death. This symptom even causes concern for patients who have recovered and have been discharged. Therefore, it is obligatory to test and monitor variations in their lungs’ function after recov...

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Autores principales: Akbar Soleymani Babadi, Alireza Kashefizadeh, Nooshin Dalili, Laya Ohadi, Abbas Gheisoori, Hossein Kazemizadeh
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Publicado: Tehran University of Medical Sciences 2021
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Acceso en línea:https://doaj.org/article/64d753f530624832869939d4c67b59ae
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spelling oai:doaj.org-article:64d753f530624832869939d4c67b59ae2021-11-29T06:16:20ZEvaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge0044-60251735-969410.18502/acta.v59i11.7780https://doaj.org/article/64d753f530624832869939d4c67b59ae2021-11-01T00:00:00Zhttps://acta.tums.ac.ir/index.php/acta/article/view/9512https://doaj.org/toc/0044-6025https://doaj.org/toc/1735-9694The most lethal adverse effect of COVID-19 is acute respiratory distress syndrome, which can lead to rapid death. This symptom even causes concern for patients who have recovered and have been discharged. Therefore, it is obligatory to test and monitor variations in their lungs’ function after recovery. In this study we evaluated the pulmonary function of 64 patients with severe COVID-19, 6 weeks to 3 months after discharge. Pulmonary function parameters were measured by spirometry and body box according to the criteria of the American Thoracic Society and under the supervision of an adult pulmonologist. According to the forced expiratory volume (FEV1) /forced vital capacity (FVC) ratio and total lung capacity (TLC) values, it was found that 3.1% of people had obstructive pattern, 40.63% of patients had restrictive pattern and 6.25% of improved individuals showed mixed pattern. Furthermore, the study of diffusion capacity of carbon monoxide (DLCO) index revealed that 13.3%, 25% and 53% of cases had mild, moderate and severe disorders of gas exchange, respectively. In addition, determining the maximum amount of inspiratory muscles (PI max) and expiratory muscles (PE max) disclosed that the rate of these two indicators in 62.5% and 71.88% of the subjects were less than 50%, respectively. In general, the results of the present study suggest that pulmonary function test and follow-up of patients' condition are not only recommended but seems to be essential after recovery due to the large percentage of patients with restricted pattern a few weeks after recovery.Akbar Soleymani BabadiAlireza KashefizadehNooshin DaliliLaya OhadiAbbas GheisooriHossein KazemizadehTehran University of Medical Sciencesarticlecovid-19discharged patientspneumoniapulmonary function test (pft)Medicine (General)R5-920ENActa Medica Iranica, Pp 669-674 (2021)
institution DOAJ
collection DOAJ
language EN
topic covid-19
discharged patients
pneumonia
pulmonary function test (pft)
Medicine (General)
R5-920
spellingShingle covid-19
discharged patients
pneumonia
pulmonary function test (pft)
Medicine (General)
R5-920
Akbar Soleymani Babadi
Alireza Kashefizadeh
Nooshin Dalili
Laya Ohadi
Abbas Gheisoori
Hossein Kazemizadeh
Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
description The most lethal adverse effect of COVID-19 is acute respiratory distress syndrome, which can lead to rapid death. This symptom even causes concern for patients who have recovered and have been discharged. Therefore, it is obligatory to test and monitor variations in their lungs’ function after recovery. In this study we evaluated the pulmonary function of 64 patients with severe COVID-19, 6 weeks to 3 months after discharge. Pulmonary function parameters were measured by spirometry and body box according to the criteria of the American Thoracic Society and under the supervision of an adult pulmonologist. According to the forced expiratory volume (FEV1) /forced vital capacity (FVC) ratio and total lung capacity (TLC) values, it was found that 3.1% of people had obstructive pattern, 40.63% of patients had restrictive pattern and 6.25% of improved individuals showed mixed pattern. Furthermore, the study of diffusion capacity of carbon monoxide (DLCO) index revealed that 13.3%, 25% and 53% of cases had mild, moderate and severe disorders of gas exchange, respectively. In addition, determining the maximum amount of inspiratory muscles (PI max) and expiratory muscles (PE max) disclosed that the rate of these two indicators in 62.5% and 71.88% of the subjects were less than 50%, respectively. In general, the results of the present study suggest that pulmonary function test and follow-up of patients' condition are not only recommended but seems to be essential after recovery due to the large percentage of patients with restricted pattern a few weeks after recovery.
format article
author Akbar Soleymani Babadi
Alireza Kashefizadeh
Nooshin Dalili
Laya Ohadi
Abbas Gheisoori
Hossein Kazemizadeh
author_facet Akbar Soleymani Babadi
Alireza Kashefizadeh
Nooshin Dalili
Laya Ohadi
Abbas Gheisoori
Hossein Kazemizadeh
author_sort Akbar Soleymani Babadi
title Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
title_short Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
title_full Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
title_fullStr Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
title_full_unstemmed Evaluation of the pulmonary function test (PFT) in patients affected by severe COVID-19 pneumonia; 6 to 12 weeks after discharge
title_sort evaluation of the pulmonary function test (pft) in patients affected by severe covid-19 pneumonia; 6 to 12 weeks after discharge
publisher Tehran University of Medical Sciences
publishDate 2021
url https://doaj.org/article/64d753f530624832869939d4c67b59ae
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