Serum exosomes from diabetic kidney disease patients promote pyroptosis and oxidative stress through the miR-4449/HIC1 pathway
Abstract Background Diabetic kidney disease (DKD) is a major contributor to end-stage renal disease. Several microRNAs (miRNAs) have been found to be enriched in exosomes of DKD patients, but it remains unclear if any of these miRNAs play an important role in the pathogenesis of DKD. Methods Exosome...
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Autores principales: | Chan Gao, Benyong Wang, Qi Chen, Ming Wang, Xiao Fei, Ning Zhao |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Publishing Group
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/64dc68e946f04f71958e411a2e740f0d |
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