NSD2 is a conserved driver of metastatic prostate cancer progression
Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis.
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Nature Portfolio
2018
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oai:doaj.org-article:64e525ee05e54b2cbb33506e939b39482021-12-02T17:32:44ZNSD2 is a conserved driver of metastatic prostate cancer progression10.1038/s41467-018-07511-42041-1723https://doaj.org/article/64e525ee05e54b2cbb33506e939b39482018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07511-4https://doaj.org/toc/2041-1723Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis.Alvaro AytesArianna GiacobbeAntonina MitrofanovaKatia RuggeroJoanna CyrtaJuan ArriagaLuis PalomeroSonia Farran-MatasMark A. RubinMichael M. ShenAndrea CalifanoCory Abate-ShenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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DOAJ |
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DOAJ |
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EN |
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Science Q |
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Science Q Alvaro Aytes Arianna Giacobbe Antonina Mitrofanova Katia Ruggero Joanna Cyrta Juan Arriaga Luis Palomero Sonia Farran-Matas Mark A. Rubin Michael M. Shen Andrea Califano Cory Abate-Shen NSD2 is a conserved driver of metastatic prostate cancer progression |
description |
Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis. |
format |
article |
author |
Alvaro Aytes Arianna Giacobbe Antonina Mitrofanova Katia Ruggero Joanna Cyrta Juan Arriaga Luis Palomero Sonia Farran-Matas Mark A. Rubin Michael M. Shen Andrea Califano Cory Abate-Shen |
author_facet |
Alvaro Aytes Arianna Giacobbe Antonina Mitrofanova Katia Ruggero Joanna Cyrta Juan Arriaga Luis Palomero Sonia Farran-Matas Mark A. Rubin Michael M. Shen Andrea Califano Cory Abate-Shen |
author_sort |
Alvaro Aytes |
title |
NSD2 is a conserved driver of metastatic prostate cancer progression |
title_short |
NSD2 is a conserved driver of metastatic prostate cancer progression |
title_full |
NSD2 is a conserved driver of metastatic prostate cancer progression |
title_fullStr |
NSD2 is a conserved driver of metastatic prostate cancer progression |
title_full_unstemmed |
NSD2 is a conserved driver of metastatic prostate cancer progression |
title_sort |
nsd2 is a conserved driver of metastatic prostate cancer progression |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/64e525ee05e54b2cbb33506e939b3948 |
work_keys_str_mv |
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