NSD2 is a conserved driver of metastatic prostate cancer progression

Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis.

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Autores principales: Alvaro Aytes, Arianna Giacobbe, Antonina Mitrofanova, Katia Ruggero, Joanna Cyrta, Juan Arriaga, Luis Palomero, Sonia Farran-Matas, Mark A. Rubin, Michael M. Shen, Andrea Califano, Cory Abate-Shen
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Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/64e525ee05e54b2cbb33506e939b3948
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spelling oai:doaj.org-article:64e525ee05e54b2cbb33506e939b39482021-12-02T17:32:44ZNSD2 is a conserved driver of metastatic prostate cancer progression10.1038/s41467-018-07511-42041-1723https://doaj.org/article/64e525ee05e54b2cbb33506e939b39482018-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07511-4https://doaj.org/toc/2041-1723Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis.Alvaro AytesArianna GiacobbeAntonina MitrofanovaKatia RuggeroJoanna CyrtaJuan ArriagaLuis PalomeroSonia Farran-MatasMark A. RubinMichael M. ShenAndrea CalifanoCory Abate-ShenNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Alvaro Aytes
Arianna Giacobbe
Antonina Mitrofanova
Katia Ruggero
Joanna Cyrta
Juan Arriaga
Luis Palomero
Sonia Farran-Matas
Mark A. Rubin
Michael M. Shen
Andrea Califano
Cory Abate-Shen
NSD2 is a conserved driver of metastatic prostate cancer progression
description Identifying cell intrinsic mechanisms promoting metastasis are necessary to develop new cancer therapeutics. Here they do cross-species computational analysis and identify nuclear receptor binding SET domain Protein 2 (NSD2) as a driver of prostate cancer metastasis.
format article
author Alvaro Aytes
Arianna Giacobbe
Antonina Mitrofanova
Katia Ruggero
Joanna Cyrta
Juan Arriaga
Luis Palomero
Sonia Farran-Matas
Mark A. Rubin
Michael M. Shen
Andrea Califano
Cory Abate-Shen
author_facet Alvaro Aytes
Arianna Giacobbe
Antonina Mitrofanova
Katia Ruggero
Joanna Cyrta
Juan Arriaga
Luis Palomero
Sonia Farran-Matas
Mark A. Rubin
Michael M. Shen
Andrea Califano
Cory Abate-Shen
author_sort Alvaro Aytes
title NSD2 is a conserved driver of metastatic prostate cancer progression
title_short NSD2 is a conserved driver of metastatic prostate cancer progression
title_full NSD2 is a conserved driver of metastatic prostate cancer progression
title_fullStr NSD2 is a conserved driver of metastatic prostate cancer progression
title_full_unstemmed NSD2 is a conserved driver of metastatic prostate cancer progression
title_sort nsd2 is a conserved driver of metastatic prostate cancer progression
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/64e525ee05e54b2cbb33506e939b3948
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